Lazio vs. Sassuolo Odds & Betting Predictions - September 14, 2025

Lazio at Sassuolo

4:00 pm

Lazio

6-5-6
0
0 - 1

Sassuolo

6-7-4
1

Lazio at Sassuolo Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Lazio
6-5-6
-0.5
-0.5-120
o2.5-103
N/A
Sassuolo
6-7-4
u2.5
+0.5-118
u2.5-120
N/A
location pinSunday 4:00 p.m.
September 14, 2025
Mapei Stadium - Citta del TricoloreReggio Emilia

Line Movement Tracker

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Lazio vs. Sassuolo Public Betting Percentages

Away Logo

Lazio

Public

Home Logo

Sassuolo

50%

Bets%

50%

Money%

Serie A Public Betting Right Arrow

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Sassuolo
9-83-56-31-58-3
Lazio
7-104-43-65-52-5

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Sassuolo
8-94-44-54-24-7
Lazio
5-123-52-75-50-7

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Sassuolo
6-73-4-13-3-31-3-25-4-2
Lazio
6-54-1-32-4-35-1-41-4-2

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Aug 29th@CREL 2-3-0.5 LO 2.5CRE +162
Aug 23rdNAPL 0-2+1 LU 2.5NAP +462
May 26th@LAZL 1-1---
May 19thCAGL 0-2---
May 12th@GENL 1-2---

Lazio vs. Sassuolo Injury Updates

Lazio Injuries

  • Pedro
    F

    Shoulder Injury

    Out Indefinitely

  • Matteo Guendouzi
    MID

    Ankle/Foot Injury

    Out Indefinitely

  • Samuel Gigot
    DEF

    Ankle/Foot Injury

    Out

  • Toma Basic
    MID

    Thigh Muscle Strain

    Out

  • Taty Castellanos
    F

    Suspended

    Out

  • Nicolo Rovella
    MID

    Rovella is doubtful with groin

    Doubtful

Sassuolo Injuries

  • Nemanja Matic
    MID

    Calf/Shin Injury

    Out Indefinitely

  • Domenico Berardi
    F

    Berardi is doubtful with thigh

    Doubtful

  • Filippo Romagna
    DEF

    Romagna is doubtful with calf

    Doubtful

  • Armand Lauriente
    F

    Back Injury

    Out

  • Edoardo Pieragnolo
    DEF

    Pieragnolo is doubtful with muscle

    Doubtful

  • Yeferson Paz Blandon
    DEF

    Paz Blandon is doubtful with muscle

    Doubtful

  • Daniel Boloca
    MID

    Boloca is doubtful with muscle

    Doubtful

Team Stats

11
Fouls
16
12
Shots
7
7
Corners
3
1
Offsides
0
0
Red Cards
0
3
Yellow Cards
6
3
Shots On Goal
2
58%
Possession Time
42%

Goalkeeping

Lazio vs. Sassuolo Odds Comparison

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Lazio at Sassuolo Team Totals

MatchupOverUnder
Lazio
6-5-6
o1.5-105
u1.5-128
Sassuolo
6-7-4
o0.5-210
u0.5+150