Pisa vs. Napoli Odds & Betting Predictions - September 22, 2025

Pisa at Napoli

6:45 pm

Pisa

1-8-8

2

2 - 3

SSC Napoli

11-4-1

3

MatchupOpenSpreadTotalMoneyline
Pisa 1-8-8	+1.5	+1.5-135	o2.5-107	N/A
Napoli 11-4-1	u2.5	-1.5-106	u2.5-123	N/A

location pin

Monday 6:45 p.m.

September 22, 2025

Stadio Diego Armando MaradonaNaples

Serie A Public Betting

Napoli are 2-3 in their last 5 games.
Napoli are 2-3 in their last 5 games against the spread
Napoli are 0-3 in their road games against the spread
The totals have gone OVER in 2 of Napoli' last 5 games
The totals have gone OVER in 1 of Napoli' 3 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Napoli	2-4	2-1	0-3	2-2	0-2
Pisa	9-8	3-6	6-2	1-2	8-6

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Napoli	2-4	1-2	1-2	2-2	0-2
Pisa	6-11	0-9	6-2	0-3	6-8

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Napoli	2-3	2-0-1	0-3	2-1-1	0-2
Pisa	1-8	1-5-3	0-3-5	1-1-1	0-7-7

date	opponent	score	spread	over/under	moneyline
Sep 13th	@FIO	W 3-1	-	O 2.5	-
Aug 30th	CAG	W 1-0	-1.5 L	U 2.5	NAP -247
Aug 23rd	@SAS	W 2-0	-1 W	U 2.5	NAP -155
May 23rd	CAG	W 2-0	-1.5 W	U 3.5	NAP -500
May 18th	@PAR	L 0-0	-1.5 L	-	PAR -221

Juan Cuadrado
DEF
Cuadrado is doubtful with muscle
Doubtful

Romelu Lukaku
F
Lukaku is out with thigh
Out
Frank Anguissa
MID
Suspended
Out
Alex Meret
GK
Meret is out with foot
Out
Stanislav Lobotka
MID
Ankle/Foot Injury
Out Indefinitely
Mathias Olivera
DEF
Calf Muscle Strain
Out Indefinitely
Eljif Elmas
MID
Elmas is injured
Out Indefinitely
Sam Beukema
DEF
Beukema is doubtful with soreness
Doubtful

See more SERIEA Injuries

Pisa

Napoli

16

Fouls

9

11

Shots

14

3

Corners

5

1

Offsides

1

0

Red Cards

0

2

Yellow Cards

1

7

Shots On Goal

6

36%

Possession Time

64%

Pisa

Goalkeeping

Napoli

Could not load odds

See more Serie A Odds

MatchupOverUnder
Pisa 1-8-8	o0.5+120	u0.5-165
Napoli 11-4-1	o1.5-190	u1.5+132