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Sassuolo vs. Inter Odds & Betting Predictions - September 21, 2025

Sassuolo at Inter

6:45 pm

Sassuolo

6-7-4
1
1 - 2

Inter

12-4
2

Sassuolo at Inter Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Sassuolo
6-7-4
+1.5
+1.5-115
o3.5+125
N/A
Inter
12-4
u2.5
-1.5-125
u3.5-163
N/A
location pinSunday 6:45 p.m.
September 21, 2025
Giuseppe MeazzaMilan

Line Movement Tracker

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Sassuolo vs. Inter Public Betting Percentages

Away Logo

Sassuolo

Public

Home Logo

Inter

50%

Bets%

50%

Money%

Serie A Public Betting Right Arrow

Betting Trends

  • Inter are 3-2 in their last 5 games.
  • Inter are 3-2 in their last 5 games against the spread
  • Inter are 2-1 in their road games against the spread
  • The totals have gone OVER in 2 of Inter' last 5 games
  • The totals have gone OVER in 0 of Inter' 3 last games at home

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Inter		3-31-22-13-20-1
Sassuolo		9-83-56-31-58-3

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Inter		2-40-32-11-41-0
Sassuolo		8-94-44-54-24-7

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Inter		4-22-12-14-10-1
Sassuolo		6-73-4-13-3-31-3-25-4-2

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Sep 13th@JUVL 3-4-0.5 LO 2.5-
Aug 31stUDIL 1-2-1.5 LO 2.5-
Aug 25thTORW 5-0-1.5 WO 2.5INT -275
May 23rd@COMW 2-0-0.5 WU 3.5INT -135
May 18thLAZW 2-2-1 LO 2.5LAZ -147

Sassuolo vs. Inter Injury Updates

Sassuolo Injuries

  • Nemanja Matic
    MID

    Calf/Shin Injury

    Out Indefinitely

  • Domenico Berardi
    F

    Berardi is doubtful with thigh

    Doubtful

  • Filippo Romagna
    DEF

    Romagna is doubtful with calf

    Doubtful

  • Armand Lauriente
    F

    Back Injury

    Out

  • Edoardo Pieragnolo
    DEF

    Pieragnolo is doubtful with muscle

    Doubtful

  • Yeferson Paz Blandon
    DEF

    Paz Blandon is doubtful with muscle

    Doubtful

  • Daniel Boloca
    MID

    Boloca is doubtful with muscle

    Doubtful

Inter Injuries

  • Henrikh Mkhitaryan
    MID

    Back Injury

    Out Indefinitely

  • Yann Sommer
    GK

    Ankle Ligaments

    Out Indefinitely

  • Raffaele Di Gennaro
    GK

    Di Gennaro is out with hand

    Out

  • Tomas Palacios
    DEF

    Palacios is doubtful with muscle

    Doubtful

See more SERIEA Injuries Right Arrow
Team Stats

8
Fouls
13
7
Shots
15
3
Corners
7
3
Offsides
2
0
Red Cards
0
1
Yellow Cards
2
5
Shots On Goal
5
40%
Possession Time
60%

Goalkeeping

Sassuolo vs. Inter Odds Comparison

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Could not load odds

See more Serie A Odds Right Arrow

Sassuolo at Inter Team Totals

MatchupOverUnder
Sassuolo
6-7-4
o0.5-140
u0.5+105
Inter
12-4
o2.5+107
u2.5-152