Mariners vs. Padres Odds & Betting Predictions - May 18, 2025
Mariners at Padres
12:40 am • ROOT Sports NWStarting Pitchers
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Mariners at Padres Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
---|---|---|---|---|
![]() Mariners 24-19 | +1.5 | +1.5-125 | o8.5+100 | +164 |
![]() Padres 27-16 | u8 | -1.5+105 | u8.5-118 | -198 |

PETCO ParkSan Diego
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Mariners vs. Padres Expert Picks

Picks Office
Last 30d: 73-84-4 (-17.8u)
SD -1.5+125
1u
Padres bounce-back loading: Pivetta owns Petco – 4-0, 1.42 ERA, 0.63 WHIP at home. Hancock allows a .322 AVG with 6.91 ERA. Padres 16-6 at home, 38-15 last 53 in SD. After 5-1 loss, expect fireworks.
Padres’ edge at the plate: .259 team AVG vs Mariners’ .237. Ranked 7th in BABIP (.304) – consistently find holes. 11th in OPS w/RISP (.746) – clutch when it counts. Averaged 8 runs/game in 5-game stretch before this series. Hancock won’t survive this order twice.
Bullpen seals it late: Padres relievers have 3.25 ERA, 1.07 WHIP. At home? Even better – 2.17 ERA. Mariners’ pen not as sharp – 3.58 ERA. Hancock unlikely to go deep, meaning more pressure on bullpen early. Padres built to dominate late innings at Petco.
Prop Odds Comparison
Line Movement Tracker
Mariners vs. Padres Public Betting Percentages
Betting Trends
- Padres are 2-3 in their last 5 games.
- Padres are 2-3 in their last 5 games against the spread
- Padres are 10-11 in their road games against the spread
- The totals have gone OVER in 3 of Padres' last 5 games
- The totals have gone OVER in 8 of Padres' 22 last games at home
Matchup History
Against the Spread (ATS) History
Over/Under History
Last 5 Matchups
Mariners vs. Padres Injury Updates

Mariners Injuries
- J.P. CrawfordIF
J.P. Crawford has been scratched Wednesday.
Out
- Victor RoblesOF
Robles is out with shoulder
Out
- Logan GilbertP
Gilbert is out with elbow
Out
- George KirbyP
Kirby is out with shoulder
Out
- Bryce MillerP
Miller is out with elbow
Out

Padres Injuries
- Joe MusgroveP
Musgrove is out for season with elbow
Out for Season
- Yu DarvishP
Darvish is out with elbow
Out
- Matt WaldronP
Waldron is out with hamstring
Out
Mariners vs. Padres Odds Comparison
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Mariners at Padres Team Totals
MatchupOverUnder | ||
---|---|---|
![]() Mariners 24-19 | N/A | N/A |
![]() Padres 27-16 | N/A | N/A |