Duke vs. Syracuse Odds & Betting Predictions - September 27, 2025

Duke at Syracuse

4:00 pm

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Duke Blue Devils

@

Syracuse Orange

MatchupOpenSpreadTotalMoneyline
Duke 1-1	N/A	N/A	N/A
Syracuse 1-1	N/A	N/A	N/A

location pin

Saturday 4:00 p.m.

September 27, 2025

JMA Wireless DomeSyracuse

No props found

NCAAF Public Betting

Syracuse are 1-1 in their last 5 games.
Syracuse are 0-1 in their last 5 games against the spread
The totals have gone OVER in 1 of Syracuse' last 2 games
The totals have gone OVER in 0 of Syracuse' 1 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Syracuse	0-1-1	0-0-1	N/A	0-0-1	0-1
Duke	0-2	0-2	N/A	0-1	0-1

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Syracuse	1-1	0-1	N/A	0-1	1-0
Duke	2-0	2-0	N/A	1-0	1-0

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Syracuse	1-1	N/A	N/A	1-0	0-1
Duke	1-1	N/A	N/A	1-0	0-1

date	opponent	score	spread	over/under	moneyline
Sep 6th	UCONN	W 27-20	-7 L	U 57.5	SYR -275
Aug 30th	@TENN	L 26-45	+13.5 L	O 51.5	TENN +425
Dec 28th	@WSU	W 52-35	-19 L	O 58.5	SYR -1050
Nov 30th	MIA	W 42-38	+12.5 W	O 68	SYR +345
Nov 23rd	UCONN	W 31-24	-10 L	O 53	SYR -360

Total

Passing

745

YDS

691

52/73

Comps/Atts

56/93

10.21

YPA

7.43

5/1

TDs/INTs

3/2

4/18

Sacks/Yards

8/56

Rushing

241

Rush Yards

147

49

Attempts

73

4.92

YPC

2.01

2

TDs

4

Turnovers

Fumbles Lost

1

Interceptions

2

Efficiency

6/8 75%

Redzone

8/11 72.7%

9/19 0%

3rd Down

10/29 0%

1/2 0%

4th Down

4/7 0%

First Downs

44

Total

48

29

Pass

31

12

Rush

15

3

Penalty

2

Misc

/

Penalties/Yards

/

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See more NCAAF Odds

MatchupOverUnder
Duke 1-1	N/A	N/A
Syracuse 1-1	N/A	N/A