Astros vs. Nationals Odds & Betting Predictions - February 27, 2026

Astros at Nationals

11:05 pm • HOU Video

Houston Astros

@

Washington Nationals

pitcher		team	era	w-l
M.Mikolas			0.00	0-0
L.McCullers			0.00	0-0

MatchupOpenSpreadTotalMoneyline
Astros 1-4	N/A	N/A	-125
Nationals 4-2	N/A	N/A	+104

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Friday 11:05 p.m.

February 27, 2026

The Ballpark of the Palm BeachesWest Palm Beach

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77°Fahrenheit

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47%Rain

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7Wind

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MLB Public Betting

Nationals are 2-3 in their last 5 games.
Nationals are 3-2 in their last 5 games against the spread
Nationals are 45-36 in their road games against the spread
The totals have gone OVER in 2 of Nationals' last 5 games
The totals have gone OVER in 40 of Nationals' 81 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Nationals	78-84	33-48	45-36	5-15	72-69
Astros	82-80	37-44	45-36	43-60	39-18

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Nationals	81-73-8	40-37-4	41-36-4	8-12	72-61-8
Astros	72-83-7	36-43-2	36-40-5	45-56-2	25-27-5

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Nationals	66-96	32-49	34-47	7-13	58-83
Astros	87-75	46-35	41-40	56-47	31-26

date	opponent	score	spread	over/under	moneyline
Feb 26th	@PHI	L 3-7	+1.5 L	U 10	PHI +130
Feb 25th	@NYY	L 0-7	+1.5 L	U 8.5	NYY +125
Feb 24th	STL	W 6-1	-1.5 W	U 8	WSH -125
Feb 23rd	PHI	W 5-5	-1.5 L	O 8.5	PHI -142
Feb 22nd	@MIA	W 16-8	+1.5 W	O 10.5	WSH +110

Hayden Wesneski
RP
Wesneski is out with elbow
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Josiah Gray
SP
Josiah Gray (elbow) scratched Tuesday.
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DJ Herz
SP
Herz is out with elbow
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MatchupOverUnder
Astros 1-4	N/A	N/A
Nationals 4-2	N/A	N/A