Cardinals vs. Astros Odds & Betting Predictions - April 18, 2026
Cardinals at Astros
11:10 pm • CARDStarting Pitchers
| pitcher | team | era | w-l | |
|---|---|---|---|---|
![]() | 6.55 | 1-3 | ||
![]() | 4.80 | 1-1 |
Cardinals at Astros Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
|---|---|---|---|---|
Cardinals 10-8 | +1.5 | +1.5-160 | o9-105 | +130 |
Astros 8-12 | u8.5 | -1.5+135 | u9-115 | -155 |

Daikin ParkHouston
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Prop Odds Comparison
Line Movement Tracker
Cardinals vs. Astros Public Betting Percentages
Betting Trends
- Astros are 2-3 in their last 5 games.
- Astros are 1-4 in their last 5 games against the spread
- Astros are 2-8 in their road games against the spread
- The totals have gone OVER in 1 of Astros' last 5 games
- The totals have gone OVER in 6 of Astros' 10 last games at home
Matchup History
Against the Spread (ATS) History
Over/Under History
Last 5 Matchups
Astros vs. Cardinals Injury Updates

Astros Injuries
- Zach DezenzoLF
Dezenzo is out with elbow
Out

Cardinals Injuries
- Jose Fermin2B
Jose Fermin has been scratched Tuesday.
Out
- Lars NootbaarLF
Nootbaar is out with heel
Out
- Hunter DobbinsSP
Dobbins is out with knee
Out
Cardinals vs. Astros Starting Lineups
Cardinals Starting Lineup| PITCHER | W-L | ERA | WHIP | K/9 | |
|---|---|---|---|---|---|
![]() | 1-1 | 4.80 | 1.533 | 4.20 |
Astros Starting Lineup| PITCHER | W-L | ERA | WHIP | K/9 | |
|---|---|---|---|---|---|
![]() | 1-0 | 5.87 | 1.304 | 9.98 |
Cardinals vs. Astros Odds Comparison
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Cardinals at Astros Team Totals
MatchupOverUnder | ||
|---|---|---|
Cardinals 10-8 | N/A | N/A |
Astros 8-12 | N/A | N/A |



