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Cardinals vs. Pirates Odds & Betting Predictions - April 27, 2026

Cardinals at Pirates

10:40 pm • CARD

St. Louis Cardinals

14-12
@

Pittsburgh Pirates

16-11
Starting Pitchers
pitcherteameraw-l
Mason Montgomery logoM.MontgomeryPittsburgh Pirates logo3.971-0
Dustin May logoD.MaySt. Louis Cardinals logo5.843-2

Cardinals at Pirates Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Cardinals
14-12
+1.5
+1.5-200
o8-116
+110
Pirates
16-11
u8.5
-1.5+165
u8-110
-131
location pinMonday 10:40 p.m.
April 27, 2026
PNC ParkPittsburgh
thermometer image69°Fahrenheit
rain image0%Rain
wind image10Wind
Cardinals vs. Pirates Expert Picks
Cam Is Money
Cam Is Money
Last 30d: 123-116-2 (+12.8u)
PIT -123
1.23u
Doug Ziefel
Doug Ziefel
Last 30d: 283-358-23 (-20.1u)
Under 8.5-112
0.56u

Prop Odds Comparison

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No props found

Line Movement Tracker

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Cardinals vs. Pirates Public Betting Percentages

Away Logo

Cardinals

Public

Home Logo

Pirates

22%

Bets%

78%

Money%

MLB Public Betting Right Arrow

Betting Trends

  • Pirates are 3-2 in their last 5 games.
  • Pirates are 3-2 in their last 5 games against the spread
  • Pirates are 9-5 in their road games against the spread
  • The totals have gone OVER in 2 of Pirates' last 5 games
  • The totals have gone OVER in 8 of Pirates' 13 last games at home

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Pirates		17-108-59-510-47-6
Cardinals		15-118-67-51-114-10

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Pirates		15-128-57-78-67-6
Cardinals		14-11-18-66-5-11-113-10-1

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Pirates		16-118-58-610-46-7
Cardinals		14-127-77-51-113-11

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Apr 26th@MILL 0-5-1.5 LU 7.5MIL +101
Apr 25th@MILW 6-3+1.5 WO 8PIT +101
Apr 24th@MILW 6-0-1.5 WU 7PIT -111
Apr 24th@TEXL 1-6+1.5 LU 7.5TEX +135
Apr 23rd@TEXW 8-4-1.5 WO 7.5PIT -119

Pirates vs. Cardinals Injury Updates

Pirates Injuries

  • Jared Jones
    SP

    Jones is out with elbow

    Out

Cardinals Injuries

  • Lars Nootbaar
    LF

    Nootbaar is out with heel

    Out

  • Hunter Dobbins
    SP

    Dobbins is out with knee

    Out

See more MLB Injuries Right Arrow
Cardinals vs. Pirates Starting Lineups
Cardinals Starting Lineup
Projected
PITCHERW-LERAWHIPK/9
Dustin May logoRD.May, P3-25.841.5407.30
HITTERSAVGOBPSLGHR
JJ Wetherholt logo1J.Wetherholt, 2B.240.370.3854
Ivan Herrera logo2I.Herrera, C.237.400.4094
Alec Burleson logo3A.Burleson, 1B.255.339.4083
Jordan Walker logo4J.Walker, RF.278.346.5678
Nolan Gorman logo5N.Gorman, DH.224.299.3533
Masyn Winn logo6M.Winn, SS.278.363.4051
Nathan Church logo7N.Church, LF.254.300.4604
Ramon Urias logo8R.Urias, 3B.170.273.3622
Victor Scott logo9V.Scott, CF.200.254.2150
Pirates Starting Lineup
Projected
PITCHERW-LERAWHIPK/9
Mason Montgomery logoLM.Montgomery, P1-03.971.50016.68
HITTERSAVGOBPSLGHR
Oneil Cruz logo1O.Cruz, CF.259.320.5188
Brandon Lowe logo2B.Lowe, 2B.247.340.5277
Bryan Reynolds logo3B.Reynolds, LF.247.383.3813
Marcell Ozuna logo4M.Ozuna, DH.165.237.2592
Ryan O'Hearn logo5R.O'Hearn, RF.330.419.5114
Nick Gonzales logo6N.Gonzales, 3B.302.341.3370
Spencer Horwitz logo7S.Horwitz, 1B.261.376.3772
Konnor Griffin logo8K.Griffin, SS.230.284.3241
Henry Davis logo9H.Davis, C.161.266.2140

Cardinals vs. Pirates Odds Comparison

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Cardinals at Pirates Team Totals

MatchupOverUnder
Cardinals
14-12
N/A
N/A
Pirates
16-11
N/A
N/A