Orioles vs. Brewers Odds & Betting Predictions - May 21, 2025

Orioles at Brewers

5:10 pm • MLB Network
8 - 4
Starting Pitchers
pitcherteameraw-l
Chad Patrick logoC.PatrickMilwaukee Brewers logo3.232-4
Tomoyuki Sugano logoT.SuganoBaltimore Orioles logo3.074-3

Orioles at Brewers Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Orioles
16-32
+1.5
-1.5+148
o8.5-118
-108
Brewers
25-26
u8.5
+1.5-179
u8.5-102
-111
location pinWednesday 5:10 p.m.
May 21, 2025
American Family FieldMilwaukee
Orioles vs. Brewers Expert Picks
Cam Is Money
Cam Is Money
Last 30d: 122-125-6 (-4.2u)
MIL -115 (Live)
0.5u
Brian Bitler
Brian Bitler
Last 30d: 77-85-0 (-19.0u)
BAL +105 (Live)
3.15u
Boomer Betz
Boomer Betz
Last 30d: 144-168-2 (-0.5u)
BAL +112
1.12u
Greg DiNardo
Greg DiNardo
Last 30d: 78-77-0 (-1.4u)
MIL -112
1.12u
💰🦡 Jake
💰�� Jake
Last 30d: 104-108-6 (-0.2u)
BAL +110
1.1u
Player Prop Savant
Player Prop Savant
Last 30d: 30-40-0 (-10.7u)
B.Turang To Record 1+ Stolen Bases Yes+415
0.4u
Top Shelf Action 🥃
Top Shelf Action 🥃
Last 30d: 221-367-12 (+15.8u)
T.Sugano o3.5 Ks-108
1u
Capper Central
Capper Central
Last 30d: 132-111-6 (+5.5u)
MIL -115
1.15u
Don’t care about series sweep.
Steak Friend
Steak Friend
Last 30d: 204-250-3 (-48.3u)
MIL -125
1.25u

Orioles vs. Brewers Previews & Analysis

  • 3 MLB Player Props for Wednesday article feature image

    3 MLB Player Props for Wednesday

    Doug Ziefel
    May 21, 2025 UTC
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Prop Odds Comparison

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Line Movement Tracker

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Orioles vs. Brewers Public Betting Percentages

Away Logo

Orioles

Public

37%

Bets%

63%

Money%

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Brewers
27-2413-1214-1216-1010-14
Orioles
15-336-179-167-218-12

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Brewers
19-29-39-15-110-14-210-15-19-13-2
Orioles
23-22-314-7-29-15-115-11-28-11-1

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Brewers
25-2615-1010-1618-86-18
Orioles
16-328-158-179-197-13

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
May 20thBALW 5-2-1.5 WU 8.5MIL -124
May 19thBALW 5-4+1.5 WO 8.5MIL -120
May 18thMINW 5-2-1.5 WU 7.5MIL -146
May 17thMINL 0-7+1.5 LU 7.5MIN +105
May 17thMINL 0-3+1.5 LU 7.5MIN -101

Brewers vs. Orioles Injury Updates

Brewers Injuries

  • Jose Quintana
    P

    Quintana is out with shoulder

    Out

  • Brandon Woodruff
    P

    Woodruff is out with shoulder

    Out

  • Easton McGee
    P

    McGee is out with arm

    Out

  • Blake Perkins
    OF

    Perkins is out with leg

    Out

  • Garrett Mitchell
    OF

    Mitchell is out with oblique

    Out

  • Aaron Ashby
    P

    Ashby is out with oblique

    Out

  • Robert Gasser
    P

    Gasser is out with elbow

    Out

Orioles Injuries

  • Albert Suarez
    P

    Suarez is out with shoulder

    Out

  • Trevor Rogers
    P

    Rogers is out with knee

    Out

  • Kyle Bradish
    P

    Bradish is out with elbow

    Out

  • Grayson Rodriguez
    P

    Rodriguez is out with elbow

    Out

  • Tyler Wells
    P

    Wells is out with elbow

    Out

Orioles vs. Brewers Box Score
Orioles Player Stats
Projected
PITCHERPCIPKER
Tomoyuki Sugano logoRT.Sugano, P88632
Andrew Kittredge logoRA.Kittredge, P8110
Gregory Soto logoLG.Soto, P9110
Felix Bautista logoRF.Bautista, P24111
Bryan Baker logoRB.Baker, P18110
Seranthony Dominguez logoRS.Dominguez, P16110
HITTERSH-ABRHRRBI
Jackson Holliday logo1J.Holliday, 2B1-6101
Adley Rutschman logo2A.Rutschman, C2-6113
Gunnar Henderson logo3G.Henderson, SS2-5300
Ryan Mountcastle logo4R.Mountcastle, DH1-6000
Ryan O'Hearn logo5R.O'Hearn, 1B4-6102
Ryan O'Hearn logo5R.O'Hearn, RF4-6102
Cedric Mullins logo6C.Mullins, CF2-4001
Emmanuel Rivera logo7E.Rivera, 3B0-3000
Emmanuel Rivera logo7E.Rivera, 1B0-3000
Heston Kjerstad logo8H.Kjerstad, LF1-5101
Dylan Carlson logo9D.Carlson, RF0-2000
Ramon Urias logo9R.Urias, PH1-3000
Ramon Urias logo9R.Urias, 3B1-3000
Jorge Mateo logo9J.Mateo, PR0-0100
Jorge Mateo logo9J.Mateo, 3B0-0100
Brewers Player Stats
Projected
PITCHERPCIPKER
Chad Patrick logoRC.Patrick, P894.271
Rob Zastryzny logoLR.Zastryzny, P170.210
Grant Anderson logoRG.Anderson, P40.200
Nick Mears logoRN.Mears, P231.202
Joel Payamps logoRJ.Payamps, P160.110
Easton McGee logoRE.McGee, P16110
Trevor Megill logoRT.Megill, P9100
Tyler Alexander logoLT.Alexander, P18103
HITTERSH-ABRHRRBI
Brice Turang logo1B.Turang, 2B0-5001
Jackson Chourio logo2J.Chourio, CF2-5001
Christian Yelich logo3C.Yelich, DH0-5000
Rhys Hoskins logo4R.Hoskins, 1B2-5111
Sal Frelick logo5S.Frelick, RF0-4100
Eric Haase logo6E.Haase, C0-4000
Jake Bauers logo7J.Bauers, LF1-3000
Daz Cameron logo7D.Cameron, PR0-0000
Andruw Monasterio logo7A.Monasterio, SS0-0000
Caleb Durbin logo8C.Durbin, 3B2-4101
Joey Ortiz logo9J.Ortiz, SS0-3000
Isaac Collins logo9I.Collins, PH0-1100
Isaac Collins logo9I.Collins, LF0-1100

Orioles vs. Brewers Odds Comparison

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Orioles at Brewers Team Totals

MatchupOverUnder
Orioles
16-32
o4.5+105
u4.5-135
Brewers
25-26
o4.5+120
u4.5-154