The Detroit Tigers host the Boston Red Sox on May 12, 2025. First pitch from Comerica Park is scheduled for 6:40 p.m. ET; the game will be broadcast on MLB Network.
This series features two teams that have been playing well lately, and both will hope to keep their momentum.
Find my MLB betting preview and Red Sox vs Tigers prediction below, as well as probable pitchers, betting trends, injury reports and more.
Boston Red Sox vs Detroit Tigers Prediction, Picks
- Tanner Houck Over 4.5 Strikeouts
- Tigers ML
Parlay Odds: +235 (Fanatics)
Red Sox vs Tigers Odds, Spread, Lines
| Red Sox Odds | ||
|---|---|---|
| Run Line | Total | Moneyline |
-1.5 +135 | 8.5 -105o / -115u | -125 |
| Tigers Odds | ||
|---|---|---|
| Run Line | Total | Moneyline |
+1.5 -160 | 8.5 -105o / -115u | +105 |
Red Sox vs Tigers Projected Pitchers
| RHP Tanner Houck (BOS) | Stat | RHP Jackson Jobe (DET) |
|---|---|---|
| 0-2 | W-L | 2-0 |
| -0.1 | fWAR (FanGraphs) | -0.1 |
| 6.10/5.05 | ERA /xERA | 4.88/4.25 |
| 5.39/4.24 | FIP / xFIP | 5.65/5.09 |
| 1.50 | WHIP | 1.48 |
| 9.8% | K-BB% | 4.1% |
| 48.9% | GB% | 44.2% |
| 98 | Stuff+ | 110 |
| 105 | Location+ | 97 |
Red Sox vs Tigers Picks, Best Bet
Red Sox Player Prop: Tanner Houck Over 4.5 Strikeouts
We're backing Tanner Houck to go over 4.5 strikeouts on Monday. Houck has covered this line in three of his last four games.
His ERA may be high, but this is partly due to allowing 11 runs in two innings to the Rays.
Since then, he's posted earned-run games of two, one, four and two, which would bring his ERA over his last four games to 2.25, a much better number.
Houck has four games this year in which he’s broken out over six strikeouts.
Back the Red Sox pitcher to get the job done on Monday.
Moneyline Pick: Tigers ML
In a small negative correlation piece, we're also taking Detroit to win.
The Tigers have had a fantastic start to their season, sitting first in the AL Central with a 26-15 record.
They're 7-3 over their last 10 games and return home on Monday.
I’m backing the Tigers to start this series hot and continue their winning ways.
Red Sox vs Tigers Same-Game Parlay
- Tanner Houck Over 4.5 Strikeouts
- Tigers ML
Parlay Odds: +235 (Fanatics)
Red Sox vs Tigers Betting Trends to Watch
