The San Diego Padres host the Chicago White Sox on May 2, 2026. First pitch from Petco Park is scheduled for 8:40 p.m. EDT. The game will be broadcast on CHSN.
The Padres are favored by -184 on the moneyline and by -1.5 (+118) on the run line. The White Sox are +154 on the moneyline and +1.5 (-142) on the run line. The total is set at 8 runs (-105 / -115)
Find my MLB picks and White Sox vs Padres prediction below, as well as probable pitchers, weather report, and more.
White Sox vs Padres Predictions & Picks
- White Sox vs Padres Pick: Miguel Vargas Over 0.5 RBI
My White Sox vs Padres best bet is a prop on Chicago Baseman Miguel Vargas. Make sure to find the best odds by checking our live MLB odds page.
White Sox vs Padres Odds, Spread, and Total
| White Sox Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+1.5 -142 | 8 -105o / -115u | +154 |
| Padres Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-1.5 +118 | 8 -105o / -115u | -184 |
- White Sox vs Padres moneyline: White Sox +154, Padres -184
- White Sox vs Padres over/under: 8 (-105o / -115u)
- White Sox vs Padres spread: Padres -1.5 (+118), White Sox +1.5 (-142)
White Sox vs Padres Pitchers
| RHP Sean Burke (CWS) | Stat | RHP Michael King (SDP) |
|---|---|---|
| 1-2 | W-L | 3-1 |
| 0.7 | fWAR (FanGraphs) | 0.5 |
| 3.21 / 3.75 | ERA / xERA | 2.41 / – |
| 3.58 / 4.12 | FIP / xFIP | 3.97 / 4.26 |
| 12.8% | K-BB% | 14.2% |
| 41.4% | GB% | 44.2% |
| .255 | BABIP | .218 |
| 95 | Stuff+ | 93 |
| 106 | Location+ | 93 |
White Sox vs Padres MLB Player Prop Pick
by Derek Carty
The Chicago White Sox come into this matchup with a 15-17 record and are 8-9 on the road. They’ve been up and down to start the season, but showed some promise in their last outing.
One bright spot has been Sean Burke, who delivered 7 1/3 scoreless innings out of the bullpen in his most recent appearance. Performances like that could give Chicago a boost heading into this game.
The San Diego Padres, meanwhile, are off to a strong 19-12 start and hold a 10-7 record at home. They’ve been solid overall and will look to keep that momentum going in front of their fans.
Michael King gets the start for San Diego and is coming off a strong performance against Arizona, where he recorded a season-high eight strikeouts. If he stays in form, the Padres should feel confident in this matchup.
White Sox vs Padres Pick and Best Bet
There may be some value on Vargas' RBIs prop for this matchup.
THE BAT X is projecting him to record 0.60 RBIs, and oddsmakers are implying 0.42. The model believes there is a 36% chance he records at least one RBI, so there is value on the over at +260.
This play is good down to at least +204.
Pick: Miguel Vargas Over 0.5 RBI
