Guardians vs A’s Prediction, Prop Pick, Odds Tonight

Guardians vs A’s Prediction, Prop Pick, Odds Tonight article feature image
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Credit: Imagn Images. Pictured: Cleveland Guardians IF Kyle Manzardo.

This article contains predictions for an old game.

The Athletics (32-46) host the Cleveland Guardians (37-37) on Saturday, June 21, 2025. First pitch from Sutter Health Park is scheduled for 10:05 p.m. ET; the game will be broadcast on NBCS-CA and Guardians TV.

Continue below to find my Guardians vs Athletics prediction and prop pick for Saturday night.

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Guardians vs A's Prediction, Prop Pick

  • Guardians vs Athletics Prop Pick: Kyle Manzardo Over 0.5 Doubles (+375, bet365)

My Guardians vs Athletics best bet is on Kyle Manzardo's doubles prop. Make sure to find the best odds by checking our live MLB odds page.


Guardians vs A's Odds

Guardians Logo
Saturday, Jun 21
10:05 p.m. ET
NBCS-CA
Athletics Logo
Guardians Odds
SpreadTotalMoneyline
-1.5
+118
9.5
-105o / -115u
-135
Athletics Odds
SpreadTotalMoneyline
+1.5
-140
9.5
-105o / -115u
+115
Odds via Caesars. Get up-to-the-minute MLB odds here.
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Alex Kolodziej’s Guardians vs Athletics Preview, Prop Pick

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Guardians Betting Preview

For this Saturday’s Guardians vs. Athletics matchup, our top MLB pick centers on Kyle Manzardo to hit a double.

My morning routine is simple: Let the dogs out, start the coffee pot, check PRO’s top picks to hit a double.

I’ve been tracking the doubles market throughout the day Saturday, and Manzardo’s odds have shifted from +350 to +375 (bet365), indicating a favorable moment to get down on this bet.

According to our projections, Manzardo is expected to record approximately 0.33 doubles in the game, which, when combined with the current price of +375, presents an estimated 7.1% value edge over the market.

While Manzardo is widely recognized for his power-hitting abilities, the market has inflated his chances of hitting a home run, especially considering Sutter Health Field is a very hitter-friendly environment.

Home run odds appear overpriced, making the double bet a sharper alternative.

Our advanced models predict Manzardo will maintain a strong slugging performance against the Athletics this weekend.

It’s also worth noting that Manzardo hit a double last Saturday for us after we recommended him at +550 odds — meaning, if he hits one again today, I will have no other choice than to call every Saturday from here on out the rest of the regular season “Kyle Manzardo Double Day.”

Pick: Kyle Manzardo Over 0.5 Doubles (+375, bet365)


Guardians vs Athletics Betting Trends


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About the Author
Alex began his career as a freelancer before becoming a columnist, reporter, and breaking news writer for FanRag Sports, and later the leading gambling writer at theScore. He joined the Action Network as a senior news editor, handling breaking news and the sports betting market's reactions. Alex also works on Action Network’s PRO projections, transforming subscription-based models into user-friendly content.

Follow Alex Kolodziej @KolodziejAlex on Twitter/X.

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