Astros vs Angels Prediction, F5 Pick, Odds

Astros vs Angels Prediction, F5 Pick, Odds article feature image
Credit:

Photo by Erik Williams-Imagn Images. Pictured: Brandon Walter

This article contains predictions for an old game.

The Los Angeles Angels (36-39) host the Houston Astros (44-32) on Saturday, June 21, 2025. First pitch from Angel Stadium is scheduled for 9:38 p.m. EDT; the game will be broadcast on FDSW.

The Astros won 3-2 in the series opener yesterday, a game that went to extra innings. Brandon Walter will take the ball for Houston today in a matchup against Los Angeles' Jose Soriano.

Find my MLB betting preview and Astros vs Angels prediction for the first five innings (F5) below.

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Astros vs Angels Prediction, F5 Pick

  • Astros vs Angels picks: First 5 Innings Under 4.5 (-140, DraftKings)

My Astros vs Angels best bet is Under 4.5 in the first five innings. Make sure to find the best odds by checking our live MLB odds page.


Astros vs Angels Odds

Astros Logo
Saturday, Jun 21
9:38 p.m. ET
MLB.TV
Angels Logo
Astros Odds
SpreadTotalMoneyline
+1.5
-202
8
-115o / -106u
+107
Angels Odds
SpreadTotalMoneyline
-1.5
+164
8
-115o / -106u
-131
Odds via DraftKings. Get up-to-the-minute MLB odds here.
DraftKings Logo

Astros vs Angels Projected Starting Pitchers

LHP Brandon Walter (HOU)StatRHP Jose Soriano (LAA)
0-0W-L4-5
0.5fWAR (FanGraphs)1.9
1.53/2.87ERA /xERA3.54/4.02
2.73/2.26FIP / xFIP3.36/3.57
0.91WHIP1.46
26.1K-BB%8.1
52.1GB%65.9
102Stuff+93
106Location+112

Astros vs Angels Betting Preview, Prediction

Jose Soriano is coming off a pair of dazzling seven-inning starts. He’s allowed three earned runs or less in nine of his past 10 appearances.

He has been much better against righties, which is important when facing the Astros since they’ll likely only have one lefty in the lineup.

Soriano has held righties to a sub-.300 wOBA and just five extra-base hits in 164 plate appearances. His strikeout rate is 5.5% better against righties than lefties, while his walk rate is down 3% to that side of the plate.

Brandon Walter is more of an unknown, but maybe he shouldn’t be. The young lefty has fired back-to-back quality starts.

He’s allowed just three earned runs in three outings. Walter’s Stuff+ and Location+ are over 100, and his CSW% is near 30%.

The Angels have struggled against lefties, ranking 25th in OPS, 29th in wOBA, and 28th in wRC+. It’s a nice spot for Walter to run his quality start streak to three.

Pick: First Half Under 4.5 (-140, DraftKings)


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Astros vs Angels Betting Trends


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