The Miami Marlins (15-26) take on the Chicago Cubs (25-18) on Wednesday, May 14, 2025. First pitch from Wrigley Field is scheduled for 7:40 p.m. ET; the game will be broadcast on Marquee and FanDuel Sports Florida.
The Cubs enter as -220 moneyline favorites with the over/under set at 7.5.
Find Marlins vs Cubs predictions for Wednesday below, as well as probable pitchers, betting trends and more.
Marlins vs Cubs Predictions, Picks
- Marlins vs Cubs Pick: Under 7.5
My Cubs vs. Marlins best bet is on both teams to stay under the total. Make sure to find the best odds by checking our live MLB odds page.
Miami Marlins vs Chicago Cubs Odds
| Marlins Odds | ||
|---|---|---|
| Run Line | Total | Moneyline |
+1.5 -115 | 7.5 -115o / -105u | +180 |
| Cubs Odds | ||
|---|---|---|
| Run Line | Total | Moneyline |
-1.5 -105 | 7.5 -115o / -105u | -220 |
Marlins vs Cubs Projected Starting Pitchers
Marlins vs Cubs Preview, Prediction
By Bet Labs
Wednesday's Marlins vs. Cubs series finale fits a historically profitable PRO System that boasts a 15.5% ROI lifetime.
The main thesis of the system is betting unders at Wrigley Field — a stadium in which weather can significantly impact scoring — when the wind is blowing in.
When the wind blows in or across and the total opens between 8–13, unders become highly valuable.
Wrigley is uniquely sensitive to weather due to field orientation and the fact that it doesn't have a dome, making it the premier ballpark for wind-based betting edges.
Marlins vs Cubs Prediction, Over/Under Pick
In addition to the Wrigley under trend, this game features a pitching matchup between Miami's Ryan Weathers and Chicago's Jameson Taillon.
Weathers is making his return to the Marlins' staff after a rehab assignment in the minors. Taillon, meanwhile, has a much bigger sample size on the season.
