All 30 MLB teams are in action, with 15 games on the slate for Tuesday, May 27.
That means there's no shortage of betting options, and our experts have come through with a multitude of MLB picks and predictions. We have a total, a moneyline, a run line and player prop picks for Giants vs Tigers, Braves vs Phillies, Twins vs Rays and Pirates vs Diamondbacks.
So, be sure to continue reading as today's MLB best bets — and a parlay of our picks — are below.
MLB Best Bets Today
The team logos in the table below represent each of the matchups that our MLB betting staff is targeting from today's slate of games. Click on the team logos for any of the matchups below to navigate to a specific bet discussed in this article.
| Game | Time (ET) | Pick |
|---|---|---|
  | 6:40 p.m. | |
  | 6:45 p.m. | |
| 6:45 p.m. | |
  | 7:05 p.m. | |
  | 9:40 p.m. | |
Specific betting recommendations come from the sportsbook offering preferred odds as of writing. Always shop for the best price using our MLB Odds page, which automatically surfaces the best lines for every game. | ||
Will Priester's Giants vs Tigers Best Bet: Back Webb in Detroit
By Will Priester
Logan Webb is having a really nice season across the board, but especially in the strikeout department.
Compared to last season, his numbers are up dramatically, and I think that'll continue tonight. There are quite a few hitters in the projected Tigers' lineup who can strike out at the clip we need, and I think Webb will be able to get us to (at least) six.
Pick: Logan Webb Over 5.5 Strikeouts (-145)
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Dylan Wilkerson's Braves vs Phillies Best Bet: Expect Runs Early
Spencer Strider is back on the bump for the Braves, making his third start since returning from his UCL injury last season.
In his most recent start, Strider went 4 1/3 innings and gave up four earned runs, including a home run. He only tallied three strikeouts and has just eight on the season. Aside from his struggles this season, Strider also has some poor matchups against the Phillies. Nick Castellanos, Bryce Harper and Brandon Marsh have all gone yard multiple times against Strider, which increases the variability in the high-scoring scoring environment.
We also see some variability with Ranger Suárez. Ozzie Albies and Austin Riley both have multiple home runs against Suárez, raising the scoring ceiling for this game.
Pick: First 5 Innings Over 4.5 (+100)
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Charlie Wright's Braves vs Phillies Best Bet: This Line is Too High
This is more like a vintage Strider number, and he's not that guy right now. Strider's velocity is down compared to his two starts in 2024 and it's down even more from his full season of work in 2023.
Strider's typically overwhelming fastball sat at 95 mph against Washington in his most recent start and he tossed a few at 93 mph in his final inning. Strider's 98 Stuff+ on the heater is a career low, and that's a metric that is reliable quickly. The 99 4-seamers he has thrown over two starts is more than enough of a sample size to judge the pitch.
The Phillies are one of the more difficult strikeout matchups for right-handed pitchers as they have the third-lowest strikeout rate vs. right handers over the past 30 days and are top 10 in OPS and wOBA in that span.
Strider's outing against the Nationals was only his second start of the season, and it was his first after a month-long absence due to a hamstring injury. He was capped at 75 pitches, and it seemed to be a firm limit as he came out for the fifth inning, walked the first hitter, then got the next one to fly out. Atlanta then went to the bullpen. The abrupt exit made it pretty clear the Braves had a pitch-count max in mind. It would be surprising to see Strider throw 90+ pitches in this one.
Pick: Spencer Strider Under 6.5 Strikeouts (-115)
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Brit Devine's Twins vs Rays Best Bet: Trust the Twins
By Brit Devine
