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Nationals vs White Sox Prediction, Pick, MLB Odds for Friday, April 24

Nationals vs White Sox Prediction, Pick, MLB Odds for Friday, April 24 article feature image
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Rick Scuteri-Imagn Images. Pictured: Munetaka Murakami

The Chicago White Sox host the Washington Nationals on April 24, 2026. First pitch from Rate Field is scheduled for 7:40 p.m. EDT. The game will be broadcast on CHSN.

The White Sox are favored by -125 on the moneyline and by -1.5 on the run line. The Nationals are +105 on the moneyline and +1.5 on the run line. The total is set at 9.5 runs.

Find my MLB picks and Nationals vs White Sox prediction below, as well as probable pitchers, weather report, and more.


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Nationals vs White Sox Prediction

  • Nationals vs White Sox Pick: Munetaka Murakami To Hit a Home Run

My Nationals vs White Sox best bet is on Munetaka Murakami to hit a home run. Make sure to find the best odds by checking our live MLB odds page.


Nationals vs White Sox Odds

Nationals Logo
Friday, Apr 24
7:40 p.m. ET
CHSN
White Sox Logo
Nationals Odds
SpreadTotalMoneyline
+1.5
-190
9.5
105o / -125u
+105
White Sox Odds
SpreadTotalMoneyline
-1.5
+160
9.5
105o / -125u
-125
Odds via bet365. Get up-to-the-minute MLB odds here.
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  • Nationals vs White Sox moneyline: Nationals +105, White Sox -125
  • Nationals vs White Sox over/under: 9.5 (+100o / -122u)
  • Nationals vs White Sox spread: Nationals +1.5 (-190), White Sox -1.5 (+160)

Nationals vs White Sox Probable Pitchers

RHP Miles Mikolas (WSN)StatLHP Bryan Hudson (CHW)
0-3W-L0-0
-0.5fWAR (FanGraphs)0.2
9.15/5.45ERA / xERA1.69/ 4.11
7.12/5.06FIP / xFIP2.77/3.82
5.1%K-BB%14.3%
45.8%GB%44.0%
.343BABIP.370
90Stuff+110
114Location+85

Nationals vs White Sox MLB Betting Preview

The Nationals are sending veteran Miles Mikolas to the mound, but his hold on a rotation spot appears tenuous at best. He's been hard hit all season long and is in danger of falling out of this rotation if this keeps up.

He had an absolute implosion where he was just eating up innings earlier in the year. I think you gave up 11 earned, and they just let him suffer out there on the bump.

They realize he's not good, trying everything they can to avoid having to pitch him. In some of his starts, they'll put an opener in front of him, and then they'll put a long man behind him, so he only has to go for maybe four innings.

The Chicago White Sox offense is currently centered around Munetaka Murakami. He's been mashing the ball this year, at least from a power perspective, with five home runs in his last six games.

Murakami is all over the news; there is a ton of hype with him. Everyone knows what he's doing right now, but we're still getting good odds on him.


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Nationals vs White Sox Pick, Betting Analysis

The Nationals announced him as the opener today, so that would line him up with Murakami in the first inning.

I'm very surprised they're offering us good enough odds to bet Murakami, given the streak that he's on.

His biggest deficiency is that he strikes out a lot, but with Mikolas, not a guy that misses bats, on the mound, this is as good a chance for Murakami to have to make a lot of contact tonight.

This is a guy who's laser-focused, with his power numbers off the charts, against a pitcher who's basically been a BP pitcher at this point.

Pick: Munetaka Murakami To Hit a Home Run

Playbook

Nationals vs White Sox Weather


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