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Yankees vs White Sox Prediction, Pick, MLB Odds for Wednesday, July 29

Yankees vs White Sox Prediction, Pick, MLB Odds for Wednesday, July 29 article feature image
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Jun 25, 2026; Boston, Massachusetts, USA; New York Yankees pitcher Cam Schlittler (31) walks to the bullpen before the start of the game against the Boston Red Sox at Fenway Park. Mandatory Credit: David Butler II-Imagn Images

The Chicago White Sox host the New York Yankees on July 29, 2026. First pitch from Rate Field is scheduled for 7:40 p.m. EDT. The game will be broadcast on CHSN.

The Yankees are favored by -150 on the moneyline and priced at +125 to cover the run-line (-1.5). The White Sox are +125 underdogs and priced at -150 to cover +1.5. The total is set at 7.5 runs.

Find my MLB picks and Yankees vs White Sox prediction below, as well as probable pitchers, weather report, and more.


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Yankees vs White Sox Prediction

  • Yankees vs White Sox Pick: Cam Schlittler to Record a Win +122 (Bet365, Play to +115)

My Yankees vs White Sox best bet is Schlittler to Record a Win. Make sure to find the best odds by checking our live MLB odds page.


Yankees vs White Sox Odds

Yankees Logo
Wednesday, Jul 29
7:40 p.m. ET
CHSN
White Sox Logo
Yankees Odds
SpreadTotalMoneyline
-1.5
+125
7.5
-110o / -110u
-150
White Sox Odds
SpreadTotalMoneyline
+1.5
-150
7.5
-110o / -110u
+125
Odds via bet365. Get up-to-the-minute MLB odds here.
bet365 Logo
  • Yankees vs White Sox moneyline: Yankees -150, White Sox +125
  • Yankees vs White Sox over/under: 7.5 (-110o/-110u)
  • Yankees vs White Sox spread: Yankees -1.5 (+125), White Sox +1.5 (-150)

Yankees vs White Sox Probable Pitchers

Cam Schlittler (RHP, NYY)StatDavis Martin (RHP, CHW)
10-6W-L9-5
4.2fWAR (FanGraphs)3.1
2.07 / 2.95ERA / xERA3.49 / 4.25
2.59 / 2.86FIP / xFIP3.07 / 3.83
25.6%K-BB%14.5%
43.0%GB%42.8%
.266BABIP.321
112Stuff+90
105Location+95

Yankees vs White Sox MLB Betting Preview

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New York Yankees Betting Preview

Despite averaging just 3.7 runs per game over their last 10 contests, the Yankees have still managed to go 7-3, finding ways to win despite the absences of Aaron Judge, Cody Bellinger, and Giancarlo Stanton.

They earned another low-scoring victory on Tuesday behind a dominant outing from Gerrit Cole and should have a good chance to secure a similar result with AL Cy Young favorite Cam Schlittler taking the mound Wednesday.

Over his last 54 innings, Schlittler has pitched to a sparkling 2.33 ERA backed by an equally impressive 2.77 xFIP, a stretch that has included several starts against offenses that were swinging the bat well.

During that span, he owns an elite 27.7% strikeout-minus-walk rate, has limited opponents to a .211 expected batting average, and posted an outstanding 116 Pitching+ rating.

The White Sox will likely stack seven lefties in their lineup Wednesday, which isn't overly concerning for Schlittler. He's been nearly as dominant against lefties this season, allowing a 2.97 xFIP while posting a 0.99 WHIP and holding them to a .332 slugging percentage.

He's also been dominant away from Yankee Stadium this season, pitching to an ERA of 1.08 across 83 and 1/3 innings on the road.

For a fairly large sample, the Yankees lineup has been among the least productive in baseball. Since June 1, New York owns a wRC+ of just 89 while striking out at a league-high 26.1% rate. It holds the fourth-lowest weighted on-base average in that span, and ranks 16th in hard-hit rate.

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Chicago White Sox Betting Preview

Following an incredible start to the season, Davis Martin has struggled to find much success, pitching to a 5.29 ERA over his last 10 starts. His underlying metrics don't suggest much positive regression, as he owns a 4.85 xERA and 4.87 xFIP during that span.

While Martin usually pitches to a fair bit of contact, his 5.9% strikeout-minus-walk rate over those outings is well below average, and opponents have produced a hard-hit rate of 42% against him.

The White Sox bullpen was expected to be sneaky good entering the season, and that take has come to fruition as White Sox relievers have pitched to an ERA of 3.94 this season and 3.05 with a 3.84 xFIP over the last 30 days.

Over the last 30 days, Chicago's lineup has hit to a wRC+ of 92, but has been more effective versus right-handed pitching, hitting to a wRC+ of 101.


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Yankees vs White Sox Pick, Betting Analysis

Schlittler appears to have a strong opportunity to further his case for the AL Cy Young in this matchup, as he takes the mound in a pitcher-friendly venue versus a White Sox offense that has started to come down to earth of late.

While New York's recent offensive play has been uninspiring, Martin's form has fallen off significantly since the start of the season and his recent underlying numbers are quite poor.

Backing the Yankees on the first five innings three-way moneyline at -115 is a reasonable option, but at +122, I see more value in backing Schlitter to record the win with the hope that New York's bullpen can protect a late lead and get across the finish line.

Pick: Cam Schlittler to Record a Win +122 (Bet365, Play to +115)


Yankees vs White Sox Weather


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