Pirates vs Cubs Odds & Prediction: Friday MLB Pick

Pirates vs Cubs Odds & Prediction: Friday MLB Pick article feature image
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Photo by Justin Berl/Getty Images. Pictured: Paul Skenes

  • The Pittsburgh Pirates and Chicago Cubs continue their NL Central series on Friday, May 17, at Wrigley Field. The game will be broadcast on MLB Network at 2:20 p.m. ET.
  • Pirates vs Cubs odds are tight as oddsmakers have the Pirates listed as -120 moneyline favorites, with an over/under of 7.5 (+102o /-122u).
  • Find MLB betting expert DJ James’ Pirates vs Cubs prediction for Paul Skenes’ second big-league start below.

Pirates vs Cubs Odds & Prediction

Pittsburgh Pirates Logo
Friday, May 17
2:20 p.m. ET
MLB Network
Chicago Cubs Logo
Pittsburgh Pirates Odds
MoneylineOver/UnderRun Line (Spread)
-120
7.5
+102o / -122u
-1.5
+145
Chicago Cubs Odds
MoneylineOver/UnderRun Line (Spread)
+100
7.5
+102o / -122u
+1.5
-175
Odds via DraftKings. Get up-to-the-minute MLB odds here.
DraftKings Logo

The Pittsburgh Pirates are slumping. As of Thursday night, the Bucs are only a game up on both the Cincinnati Reds and St. Louis Cardinals in the NL Central. Pittsburgh, however, has a light at the end of the tunnel because its pitching staff is decent. Paul Skenes will throw, once again, against the Chicago Cubs — this time at Wrigley Field on Friday afternoon.

Kyle Hendricks will be Skenes' counterpart. The Cubs right-hander put together a nice performance against the Pirates on Mother's Day.

The Cubs are about average when it comes to hitting righties, and Pittsburgh is flailing now. With that being said, the under could be in play with the wind blowing in at Wrigley Field on Friday. Find my MLB betting preview for Skenes' second MLB start, which includes my Pirates vs Cubs prediction on the over/under.


Check out our MLB Betting Hub for more previews from today's slate.

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Pittsburgh Pirates

Skenes is one of the most highly-touted pitching prospects ever, but he did not fare well in his MLB debut. He allowed three runs six hits and two walks over four innings, though he did strike out seven.

He gets a chance at redemption on Friday. This year in the minors, Skenes held a strikeout rate above 40% with a walk rate under 8%. His xwOBA was an unbelievable .214.

On offense, the outlook isn't so bright for the Bucs. They have a 59 wRC+ and a 25.3% strikeout rate over the last month against right-handed pitching. Pittsburgh only has four hitters above a .350 xwOBA off of righties in that timeframe, with the rest of the active roster placing under .285.

In relief, the Bucs have a 4.55 xFIP over the last month. Walks have been a major issue for their relief staff as a unit at over 12%. Kyle Nicolas, David Bednar and Hunter Stratton are under the 4.00 mark, so we'll see if Skenes can make it through five innings untouched this time.

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Chicago Cubs

Hendricks was unbelievably bad before hitting the injured list with a lower back strain on April 23. However, given the Pirates' hitting struggles, he's shown he can at least take them on. The wind blowing in is an added bonus for the soft-tossing righty.

Hendricks ranks in the 87th percentile in Hard-Hit Rate and Average Exit Velocity, and his ground-ball rate is above average. If he limit the walks, he should be more than fine against Pittsburgh.

The Cubs have a 94 wRC+, 9.2% walk rate and 24.4% strikeout rate off of righties over the last month. They are patient, but Skenes should be able to miss some bats. Chicago has six batters eclipsing a .335 xwOBA in that timeframe against righties, but there is a steep drop-off in the rest of the batting order.

The Cubs relief staff has had their question marks this year. However, they have a 3.97 xFIP over the last month, so things are looking up. They only have a few active arms under a 4.00 xFIP as they have been decimated by injuries. That said, this should be enough against a weak Pittsburgh lineup.

The +1400 Same Game Parlay for Pirates vs. Cubs Image

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Pirates vs Cubs

Betting Pick & Prediction

Skenes should get better, and it could start Friday with another shot at Chicago. Hendricks will remain steady with the weaker lineup against him and continue to manufacture grounders and weak contact.

Both bullpens should have enough to lock down the game. This should be a low-scoring game if the forecast holds with the wind, especially. Take the under from 8 to 7.5.

Pick: Under 8 (-104 via FanDuel)

About the Author
D.J. is a contributor for The Action Network. He specializes in baseball analytics and baseball betting insight.

Follow D.J. James @cwsdjt on Twitter/X.

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