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White Sox vs Mariners Prediction, Odds: Expert MLB Prop Pick for Tonight’s Game

White Sox vs Mariners Prediction, Odds: Expert MLB Prop Pick for Tonight’s Game article feature image
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Pictured: Seattle Mariners starting pitcher Bryan Woo. (Credit: Kevin Ng-Imagn Images)

The Seattle Mariners host the Chicago White Sox on May 18, 2026. First pitch from T-Mobile Park is scheduled for 9:40 p.m. EDT. The game will be broadcast on CHSN.

The Mariners are favored by -174 on the moneyline and by -1.5 on the run line. The White Sox are +146 on the moneyline and +1.5 on the run line. The total is set at 7.5 runs.

Find my MLB picks and White Sox vs Mariners prediction below, as well as probable pitchers, weather report, and more.


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White Sox vs Mariners Prediction

  • White Sox vs Mariners Pick: Bryan Woo 7+ Strikeouts (+112)

My White Sox vs Mariners best bet is on Bryan Woo to record 7+ strikeouts. Make sure to find the best odds by checking our live MLB odds page.


White Sox vs Mariners Odds

White Sox Logo
Monday, May 18
9:40 p.m. ET
CHSN
Mariners Logo
White Sox Odds
SpreadTotalMoneyline
+1.5
-154
7.5
-104o / -118u
+146
Mariners Odds
SpreadTotalMoneyline
-1.5
+128
7.5
-104o / -118u
-174
Odds via FanDuel. Get up-to-the-minute MLB odds here.
FanDuel Logo
  • White Sox vs Mariners moneyline: White Sox +146, Mariners -174
  • White Sox vs Mariners over/under: 7.5 (-104o / -118u)
  • White Sox vs Mariners spread: Mariners -1.5 (+126 ), White Sox +1.5 (-154)

White Sox vs Mariners Probable Pitchers

Noah Schultz (CHW)StatRHP Bryan Woo (SEA)
2-2W-L3-2
0.4fWAR (FanGraphs)1.2
4.91/4.82ERA / xERA3.91/3.28
4.36/5.10FIP / xFIP3.47/4.13
4.0%K-BB%17.5%
35.1%GB%30.3%
.224BABIP.253
97Stuff+110
96Location+109

White Sox vs Mariners MLB Betting Preview

Two pretty interesting pitchers are going in this one. The giant Noah Schultz heads to Seattle to face Bryan Woo. Schultz hasn't had the best time in the majors so far, posting a 4.91 ERA and a 1.36 WHIP. His problem has been walks.

He's issued 21 free passes in 29.1 innings. He doesn't have a single pitch with a ball rate below the league average. It looks pretty disastrous for him from a command standpoint.

But Bryan Woo is my focal point. He's my projection model's top fantasy-point projection arm on the board tonight against this White Sox lineup that can strike out a bunch.

This game being in Seattle matters. It's been favorable for pitchers for quite some time. The Mariners staff isn't having its usual level of success this year, but nothing about the park has changed, and we're still seeing more strikeouts in games played there — a 24% strikeout rate in Seattle games compared to 22% everywhere else.


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White Sox vs Mariners Pick, Betting Analysis

Woo enters this matchup with back-to-back nine-strikeout games and 28 total whiffs across those outings against the Braves and Astros.

The White Sox are second in the league in home runs now, so you can never fully count on a starting pitcher to stay under an earned-runs prop. But opposing starters are usually piling up strikeouts and working efficiently if they're throwing enough strikes to force the White Sox to swing the bats.

This is an offense that likes to walk and likes to hit the long ball. Woo is going to come right after them, and that should work in his favor tonight.

Pick: Bryan Woo 7+ Strikeouts (+112)


White Sox vs Mariners Weather


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Jon AndersonVerified Action Expert

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