Louisville vs. Cincinnati Odds & Betting Predictions - November 21, 2025
Louisville at Cincinnati
11:30 pm • ESPN2Louisville at Cincinnati Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
|---|---|---|---|---|
Louisville 10-2 | -8.5-110 | o163.5-110 | -470 | |
Cincinnati 7-5 | +8.5-110 | u163.5-115 | +355 | |

Fifth Third ArenaCincinnati
Louisville vs. Cincinnati Expert Picks
Cam Is Money
Last 30d: 110-95-3 (+6.9u)
LOU -125 (Live)
0.8u
CTO
Last 30d: 17-16-0 (+3.2u)
CIN +5.5 (1H)-110
1.82u
Babs .
Last 30d: 94-65-0 (+23.4u)
Under 164.5-115
0.87u
Will Brinson
Last 30d: 26-23-0 (+11.6u)
LOU -8.5-111
1u
Sean Paul
Last 30d: 39-56-1 (-19.2u)
CIN +8.5-110
1u
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Louisville vs. Cincinnati Previews & Analysis
Prop Odds Comparison
Line Movement Tracker
Louisville vs. Cincinnati Public Betting Percentages
Betting Trends
- Cincinnati are 2-3 in their last 5 games.
- Cincinnati are 2-3 in their last 5 games against the spread
- Cincinnati are 1-2 in their road games against the spread
- The totals have gone OVER in 1 of Cincinnati' last 5 games
- The totals have gone OVER in 2 of Cincinnati' 9 last games at home
Matchup History
Against the Spread (ATS) History
| overall | home | away | favorite | underdog | |
|---|---|---|---|---|---|
| 4-8 | 3-6 | 1-2 | 3-4 | 1-3 | |
| 8-4 | 6-2 | 2-2 | 5-1 | 0-1 |
Over/Under History
| overall | home o/u | away o/u | favorite o/u | underdog o/u | |
|---|---|---|---|---|---|
| 3-9 | 2-7 | 1-2 | 1-6 | 1-3 | |
| 6-6 | 4-4 | 2-2 | 4-2 | 0-1 |
Straight-Up (ML) History
| overall | home | away | favorite | underdog | |
|---|---|---|---|---|---|
| 7-5 | N/A | N/A | 6-1 | 0-4 | |
| 10-2 | N/A | N/A | 5-1 | 0-1 |
Last 5 Matchups
Team Stats
21-56 (38%)
Field Goals
23-62 (37%)
24-28 (86%)
Free Throws
10-16 (63%)
8-28 (29%)
3P
8-29 (28%)
35
Rebounds
35
13
Assists
19
13
Turnovers
13
9
Steals
5
4
Blocks
7
23
Fouls
19
Louisville vs. Cincinnati Odds Comparison
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Louisville at Cincinnati Team Totals
MatchupOverUnder | ||
|---|---|---|
Louisville 10-2 | o87.5-115 | u87.5-115 |
Cincinnati 7-5 | o77.5-110 | u77.5-120 |




