Louisville vs. Hokies Odds & Betting Predictions - November 1, 2025
Louisville at Hokies
7:00 pm • The CWLouisville at Hokies Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
|---|---|---|---|---|
Louisville 8-4 | -15.5 | -10.5-110 | o52.5-112 | -395 |
Hokies 3-9 | u52.5 | +10.5-110 | u52.5-110 | +310 |

Lane StadiumBlacksburg
Louisville vs. Hokies Expert Picks
Will Brinson
Last 30d: 28-33-2 (+1.6u)
LOU -10-112
1u
Top Shelf Action 🥃
Last 30d: 119-134-11 (+1.2u)
Under 53.5-110
0.82u
3.13% ev play to -117
Louisville vs. Hokies Previews & Analysis
Prop Odds Comparison
Line Movement Tracker
Louisville vs. Hokies Public Betting Percentages
Betting Trends
- Hokies are 1-4 in their last 5 games.
- Hokies are 1-4 in their last 5 games against the spread
- Hokies are 1-3 in their road games against the spread
- The totals have gone OVER in 2 of Hokies' last 5 games
- The totals have gone OVER in 5 of Hokies' 7 last games at home
Matchup History
Against the Spread (ATS) History
| overall | home | away | favorite | underdog | |
|---|---|---|---|---|---|
| 3-9 | 2-5 | 1-3 | 1-4 | 2-5 | |
| 4-8 | 1-7 | 3-1 | 2-7 | 2-1 |
Over/Under History
| overall | home o/u | away o/u | favorite o/u | underdog o/u | |
|---|---|---|---|---|---|
| 5-7 | 5-2 | 0-4 | 4-1 | 1-6 | |
| 5-7 | 4-4 | 1-3 | 5-4 | 0-3 |
Straight-Up (ML) History
| overall | home | away | favorite | underdog | |
|---|---|---|---|---|---|
| 3-9 | N/A | N/A | 2-3 | 1-6 | |
| 8-4 | N/A | N/A | 6-3 | 2-1 |
Last 5 Matchups
Team Stats
136
YDS
76
19/28
Comps/Atts
11/24
4.857142857142857
YPA
3.1666666666666665
1/1
TDs/INTs
1/0
1/5
Sacks/Yards
0/0
6/52
Penalties/Yards
5/46
Louisville vs. Hokies Odds Comparison
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Louisville at Hokies Team Totals
MatchupOverUnder | ||
|---|---|---|
Louisville 8-4 | o31.5-106 | u31.5-123 |
Hokies 3-9 | o20.5-119 | u20.5-108 |






