Louisville vs. Hokies Odds & Betting Predictions - November 1, 2025

Louisville at Hokies

7:00 pm • The CW
28 - 16

Louisville at Hokies Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Louisville
8-4
-15.5
-10.5-110
o52.5-112
-395
Hokies
3-9
u52.5
+10.5-110
u52.5-110
+310
location pinSaturday 7:00 p.m.
November 01, 2025
Lane StadiumBlacksburg
Louisville vs. Hokies Expert Picks
Will Brinson
Will Brinson
Last 30d: 28-33-2 (+1.6u)
LOU -10-112
1u
Top Shelf Action 🥃
Top Shelf Action 🥃
Last 30d: 119-134-11 (+1.2u)
Under 53.5-110
0.82u
3.13% ev play to -117

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See more NCAAF Coverage Right Arrow

Prop Odds Comparison

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No props found

Line Movement Tracker

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Louisville vs. Hokies Public Betting Percentages

Away Logo

Louisville

Public

51%

Bets%

49%

Money%

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Hokies
3-92-51-31-42-5
Louisville
4-81-73-12-72-1

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Hokies
5-75-20-44-11-6
Louisville
5-74-41-35-40-3

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Hokies
3-9N/AN/A2-31-6
Louisville
8-4N/AN/A6-32-1

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Oct 24thCALW 42-34-6 WO 50.5VT -225
Oct 11th@GTL 20-35+14 LU 55.5GT +440
Oct 4thWFL 23-30-5 LO 51WF -205
Sep 27th@NCSTW 23-21+9.5 WU 57.5VT +290
Sep 20thWOFW 38-6-34.5 LU 51.5-
Team Stats
371
Total Yards
240
62
Total Plays
64
5.983870967741935
Yards Per Play
3.75
136
YDS
76
19/28
Comps/Atts
11/24
4.857142857142857
YPA
3.1666666666666665
1/1
TDs/INTs
1/0
1/5
Sacks/Yards
0/0
235
Rush Yards
164
34
Attempts
40
6.911764705882353
YPC
4.1
3
TDs
1
0
Fumbles Lost
0
1
Interceptions
0
1/2 50%
Redzone
2/2 100%
4/11 0%
3rd Down
4/15 0%
0/1 0%
4th Down
0/2 0%

First Downs

18
Total
16
6
Pass
5
11
Rush
9
1
Penalty
2
6/52
Penalties/Yards
5/46

Louisville vs. Hokies Odds Comparison

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Louisville at Hokies Team Totals

MatchupOverUnder
Louisville
8-4
o31.5-106
u31.5-123
Hokies
3-9
o20.5-119
u20.5-108