College football picks are once again top of mind for sports bettors as the 2025 season kicks off with a nine-game Week 0 slate on Saturday.
With the help of our cutting-edge Action PRO tools and betting software (now available for $9.99/week until Sunday) we're slicing through the noise to pinpoint the best college football picks for Week 0, including one spread or over/under prediction for each of today's nine games.
So without further ado, let's dive into today's college football Week 0 slate, including the picks that the sharpest sports bettors are making on Saturday, August. 23.
9 College Football Picks for Saturday, Week 0
Kansas State vs. Iowa State Pick
Live college football odds list Kansas State as a 3-point spread favorite against Iowa State in Dublin.
In addition, 60% of spread tickets have come in on the Wildcats as well.
