The Florida Gators take on the Ole Miss Rebels in Oxford, Mississippi. Kickoff is set for 7 p.m. ET on ESPN.
Ole Miss is favored by 14 points on the spread with a moneyline of -575. Florida, meanwhile, enters as a +14 favorite and is +425 on the moneyline to pull off the upset. The over/under sits at 53.5 total points.
Here’s my Florida vs. Ole Miss prediction and college football picks for Saturday, November 15.
Florida vs Ole Miss Prediction
- Florida vs. Ole Miss Pick: 1Q Over 10.5 (Play to 12.5)
My Ole Miss vs. Florida best bet is on the first-quarter over. Find the best line available on our live NCAAF odds page.
Florida vs Ole Miss Odds
| Florida Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+14 -110 | 53.5 -110o / -110u | +425 |
| Ole Miss Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-14 -110 | 53.5 -110o / -110u | -575 |
- Florida vs Ole Miss Spread: Ole Miss -14, Florida +14
- Florida vs Ole Miss Over/Under: 53.5 Points
- Florida vs Ole Miss Moneyline: Florida +425, Ole Miss -575
Florida vs Ole Miss College Football Betting Preview
Florida Gators Betting Preview: Out of Sync
After hanging tough with Georgia and defeating Texas, the Florida Gators bottomed out last week in a 38-7 loss to Kentucky.
This Gators offense has been plagued by the little things, which have added up to completely derail their offense, as we saw last week.
Florida struggles to sustain drives, ranking 109th in third-down conversion rate. Meanwhile, quarterback DJ Lagway has been a failed gunslinger, throwing more interceptions than passing touchdowns this season.
These issues only amplify the Gators' overall inefficiency, as they rank 98th in yards per pass and 96th in yards per rush.
This offense is in its worst form yet and now finds itself up against an Ole Miss defense that's solid against the pass — the Gators' only glimmer of offensive hope.
Ole Miss Rebels Betting Preview: Chambliss Sparks the Rebs
We know the Ole Miss defense should feast on a Gators offense that's down and out, but its offense is the key to our angle.
The Rebels run their offense at the 14th-fastest pace in the country, and that's only amplified by the dual-threat ability of quarterback Trinidad Chambliss.
Ole Miss is in a great spot to start fast against the Gators. We should see the Rebels run effectively on early downs with either Chambliss or Kewan Lacy.
That will then open things up down the field for Chambliss and his quartet of field-stretching receivers.
With the Gators offense struggling, expect the Rebels to put pressure on their defense early and find their way into the end zone multiple times in the first 15 minutes.

Florida vs Ole Miss Pick, Betting Analysis
We've seen the total rise in this matchup throughout the week, and it's a clear indication of how Ole Miss can dominate early. We have yet to see an offensive hiccup from the Rebels, and the Gators are in no shape to provide a barrier.
Take the first-quarter over, as Ole Miss has the potential to do it itself.
Pick: 1Q Over 10.5 (Play to 12.5)




















