Astros vs. Angels Odds & Betting Predictions - June 21, 2025

Astros at Angels

1:38 am • SCHN
3 - 2
Starting Pitchers
pitcherteameraw-l
Yusei Kikuchi logoY.KikuchiLos Angeles Angels logo3.012-6
Hunter Brown logoH.BrownHouston Astros logo1.888-3

Astros at Angels Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Astros
44-32
-1.5
-1.5+102
o8-110
-171
Angels
36-39
u8
+1.5-122
u8-106
+141
location pinSaturday 1:38 a.m.
June 21, 2025
Angel StadiumAnaheim
Astros vs. Angels Expert Picks
Boomer Betz
Boomer Betz
Last 30d: 200-210-4 (+4.8u)
HOU -110 (Live)
1.82u
Capper Central
Capper Central
Last 30d: 122-91-6 (+14.4u)
HOU -165
1u
Model + posting trend on Twitter
Picks Office
Picks Office
Last 30d: 90-75-2 (+15.0u)
LAA +1.5-105
0.95u
Follow @PicksOffice on X to read the full writeup
Bet Labs
Bet Labs
Last 30d: 48-47-1 (-3.7u)
LAA +140
0.36u
Boomer Betz
Boomer Betz
Last 30d: 200-210-4 (+4.8u)
H.Brown o4.5 Hits Allowed-115
1u
Austin Pendergrass
Austin Pendergrass
Last 30d: 87-115-1 (-14.8u)
HOU -168
0.3u
Kyle Murray
Kyle Murray
Last 30d: 70-88-2 (+16.7u)
H.Brown To Record 9+ Strikeouts Yes+275
0.75u
H.Brown To Record 10+ Strikeouts Yes+525
0.5u
H.Brown To Record 11+ Strikeouts Yes+750
0.3u
H.Brown To Record 12+ Strikeouts Yes+1400
0.15u
H.Brown o6.5 Ks-140
1.4u

Astros vs. Angels Previews & Analysis

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    Friday's Game Juiced with Home Run Edges

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  • Friday's MLB Best Bets article feature image

    Friday's MLB Best Bets

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Prop Odds Comparison

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Line Movement Tracker

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Astros vs. Angels Public Betting Percentages

Away Logo

Astros

Public

80%

Bets%

20%

Money%

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Angels
38-3717-1521-223-1134-26
Astros
41-3522-1819-1725-2916-5

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Angels
37-36-214-16-223-205-8-132-27-1
Astros
30-43-316-2414-19-325-28-14-15-2

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Angels
36-3915-1721-228-627-33
Astros
44-3227-1317-1932-2212-9

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Jun 19th@NYYL 3-7+1.5 LU 10.5NYY +230
Jun 18th@NYYW 3-2+1.5 WU 9.5LAA +207
Jun 17th@NYYW 4-0+1.5 WU 9LAA +198
Jun 16th@NYYW 1-0+1.5 WU 8LAA +165
Jun 15th@BALL 2-11-1.5 LO 8.5BAL -105

Angels vs. Astros Injury Updates

Angels Injuries

  • Jorge Soler
    RF

    Soler is out with back

    Out

  • Anthony Rendon
    3B

    Rendon is out with hip

    Out

Astros Injuries

  • Lance McCullers
    SP

    Lance McCullers (foot) has been scratched Monday. Ryan Gusto will start for the Astros.

    Out

  • Taylor Trammell
    LF

    Trammell is out with calf

    Out

  • Cristian Javier
    SP

    Javier is out with elbow

    Out

  • Luis Garcia
    SP

    Garcia is out with elbow

    Out

  • Pedro Leon
    RF

    Leon is out with knee

    Out

  • J.P. France
    SP

    France is out with shoulder

    Out

  • Hayden Wesneski
    RP

    Wesneski is out with elbow

    Out

  • Spencer Arrighetti
    SP

    Arrighetti is out with thumb

    Out

Astros vs. Angels Box Score
Astros Player Stats
Projected
PITCHERPCIPKER
Hunter Brown logoRH.Brown, P87541
Shawn Dubin logoRS.Dubin, P170.110
Bryan King logoLB.King, P271.231
Bryan Abreu logoRB.Abreu, P30120
Josh Hader logoLJ.Hader, P9110
Bennett Sousa logoLB.Sousa, P10110
HITTERSH-ABRHRRBI
Jeremy Pena logo1J.Pena, SS3-4111
Isaac Paredes logo2I.Paredes, 3B2-4111
Jose Altuve logo3J.Altuve, DH0-4000
Yainer Diaz logo4Y.Diaz, C0-5000
Cam Smith logo5C.Smith, RF1-4000
Christian Walker logo6C.Walker, 1B0-4000
Jake Meyers logo7J.Meyers, CF2-4000
Cooper Hummel logo8C.Hummel, LF1-3000
Luis Guillorme logo8L.Guillorme, 2B0-0000
Victor Caratini logo8V.Caratini, PH0-1000
Shay Whitcomb logo8S.Whitcomb, 2B0-0000
Mauricio Dubon logo9M.Dubon, 2B0-4100
Mauricio Dubon logo9M.Dubon, LF0-4100
Angels Player Stats
Projected
PITCHERPCIPKER
Yusei Kikuchi logoLY.Kikuchi, P103792
Reid Detmers logoLR.Detmers, P22110
Kenley Jansen logoRK.Jansen, P17100
Hunter Strickland logoRH.Strickland, P19110
HITTERSH-ABRHRRBI
Zach Neto logo1Z.Neto, SS0-4000
Nolan Schanuel logo2N.Schanuel, 1B0-5000
Mike Trout logo3M.Trout, DH0-2000
Taylor Ward logo4T.Ward, LF1-5000
Travis d'Arnaud logo5T.d'Arnaud, C1-5000
Jo Adell logo6J.Adell, CF1-4111
LaMonte Wade logo7L.Wade, RF0-2000
Logan O'Hoppe logo7L.O'Hoppe, PH0-1000
Gustavo Campero logo7G.Campero, RF1-1000
Luis Rengifo logo8L.Rengifo, 3B1-3000
Christian Moore logo9C.Moore, 2B1-4111

Astros vs. Angels Odds Comparison

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Astros at Angels Team Totals

MatchupOverUnder
Astros
44-32
o4.5-108
u4.5-120
Angels
36-39
o3.5+107
u3.5-137