Athletics vs. Pirates Odds & Betting Predictions - September 21, 2025

Athletics at Pirates

5:35 pm • NBCS-CA

Athletics

0

0 - 11

Pittsburgh Pirates

11

pitcher		team	era	w-l
M.Burrows			3.94	2-4
M.Spence			5.10	3-6

MatchupOpenSpreadTotalMoneyline
Athletics 0-0	+1.5	-1.5+172	o8.5-108	+100
Pirates 0-0	u8.5	+1.5-193	u8.5-113	-121

location pin

Sunday 5:35 p.m.

September 21, 2025

PNC ParkPittsburgh

No props found

MLB Public Betting

Pirates are 3-2 in their last 5 games.
Pirates are 4-1 in their last 5 games against the spread
Pirates are 42-39 in their road games against the spread
The totals have gone OVER in 1 of Pirates' last 5 games
The totals have gone OVER in 33 of Pirates' 81 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Pirates	90-72	48-33	42-39	19-26	69-45
Athletics	86-76	39-42	47-34	14-24	70-50

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Pirates	61-92-9	33-43-5	28-49-4	17-26-2	42-65-7
Athletics	77-77-8	40-39-2	37-38-6	14-22-2	61-53-6

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Pirates	71-91	44-37	27-54	22-23	48-66
Athletics	76-86	36-45	40-41	17-21	56-64

date	opponent	score	spread	over/under	moneyline
Sep 20th	ATH	W 2-0	+1.5 W	U 8	PIT -107
Sep 19th	ATH	L 3-4	+1.5 W	U 8.5	ATH -107
Sep 17th	CHC	L 4-8	+1.5 L	O 7.5	CHC +121
Sep 16th	CHC	L 1-4	-1.5 L	U 6.5	CHC -131
Sep 15th	CHC	L 0-4	+1.5 L	U 8	CHC +102

Luis Medina
SP
Medina is out with elbow
Out

Johan Oviedo
SP
Oviedo is questionable with elbow
Questionable
Endy Rodriguez
1B
Rodriguez is out with elbow
Out
Jared Jones
SP
Jones is out with elbow
Out

See more MLB Injuries

PITCHER		PC	IP	K	ER
RM.Spence, P		64	3.1	1	6
RO.Bido, P		63	3.2	6	3
RS.McGough, P		24	1	1	1

HITTERS	H-AB	R	HR	RBI
1L.Butler, CF	0-3	0	0	0
1C.Thomas, CF	0-1	0	0	0
2B.Rooker, DH	2-4	0	0	0
3N.Kurtz, 1B	1-3	0	0	0
3B.Harris, 1B	1-1	0	0	0
4T.Soderstrom, LF	1-2	0	0	0
4J.Bleday, PH	0-2	0	0	0
4J.Bleday, LF	0-2	0	0	0
5J.Wilson, SS	0-4	0	0	0
5M.Muncy, 3B	0-0	0	0	0
6C.Cortes, RF	1-4	0	0	0
7D.Hernaiz, 3B	0-4	0	0	0
7D.Hernaiz, SS	0-4	0	0	0
8W.MacIver, C	1-4	0	0	0
9M.Schuemann, 2B	1-3	0	0	0

PITCHER		PC	IP	K	ER
RM.Burrows, P		74	4	3	0
RC.Mlodzinski, P		48	3	3	0
RY.Ramirez, P		13	1	1	0
RD.Moreta, P		15	1	2	0

HITTERS	H-AB	R	HR	RBI
1O.Cruz, CF	1-5	1	0	2
2J.Triolo, 3B	4-5	2	1	3
2C.Devanney, 3B	0-0	0	0	0
3B.Reynolds, RF	1-3	1	0	0
3A.Canario, RF	1-1	0	0	0
4S.Horwitz, 1B	0-3	1	0	1
5A.McCutchen, DH	1-4	1	0	1
6N.Gonzales, SS	1-4	0	0	1
7J.Suwinski, LF	1-4	1	0	0
8J.Bart, C	4-4	2	1	3
9N.Yorke, 2B	1-4	2	0	0

Could not load odds

See more MLB Odds

MatchupOverUnder
Athletics 0-0	o3.5-141	u3.5+111
Pirates 0-0	o4-116	u4-110