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Guardians vs. Tigers Odds & Betting Predictions - September 17, 2025

Guardians at Tigers

10:40 pm • FDSDET
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Cleveland Guardians

79-71
@

Detroit Tigers

85-66
Starting Pitchers
pitcherteameraw-l
Jack Flaherty logoJ.FlahertyDetroit Tigers logo4.698-13
Gavin Williams logoG.WilliamsCleveland Guardians logo3.1610-5

Guardians at Tigers Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Guardians
79-71
+1.5
+1.5-175
o8-115
+123
Tigers
85-66
u8.5
-1.5+145
u8-106
-150
location pinWednesday 10:40 p.m.
September 17, 2025
Comerica ParkDetroit
thermometer image78°Fahrenheit
rain image0%Rain
wind image4Wind

Prop Odds Comparison

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No props found

Line Movement Tracker

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Guardians vs. Tigers Public Betting Percentages

Away Logo

Guardians

Public

Home Logo

Tigers

46%

Bets%

54%

Money%

MLB Public Betting Right Arrow

Betting Trends

  • Tigers are 1-4 in their last 5 games.
  • Tigers are 1-4 in their last 5 games against the spread
  • Tigers are 31-44 in their road games against the spread
  • The totals have gone OVER in 4 of Tigers' last 5 games
  • The totals have gone OVER in 39 of Tigers' 76 last games at home

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Tigers		72-7941-3531-4449-5723-20
Guardians		79-7137-3842-3331-3147-38

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Tigers		80-64-739-32-541-32-255-45-624-18-1
Guardians		65-79-634-38-331-41-331-30-133-47-5

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Tigers		85-6646-3039-3664-4221-22
Guardians		79-7141-3438-3740-2239-46

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Sep 16thCLEL 5-7-1.5 LO 8CLE -145
Sep 14th@MIAW 2-0-1.5 WU 9DET -135
Sep 13th@MIAL 4-6-1.5 LO 8.5MIA -132
Sep 12th@MIAL 2-8-1.5 LO 7MIA -199
Sep 11th@NYYL 3-9+1.5 LO 8.5NYY +140

Guardians vs. Tigers Injury Updates

Guardians Injuries

  • Ben Lively
    SP

    Lively is out with elbow

    Out

  • John Means
    SP

    Means is out with elbow

    Out

Tigers Injuries

  • Alex Cobb
    SP

    Cobb is out with hip

    Out

  • Jose Urquidy
    SP

    Urquidy is out with arm

    Out

  • Reese Olson
    SP

    Olson is out with shoulder

    Out

  • Ty Madden
    SP

    Madden is out with shoulder

    Out

See more MLB Injuries Right Arrow
Guardians vs. Tigers Starting Lineups
Guardians Starting Lineup
Projected
PITCHERW-LERAWHIPK/9
Gavin Williams logoRG.Williams, P10-53.161.2898.73
HITTERSAVGOBPSLGHR
Steven Kwan logo1S.Kwan, LF.274.334.37710
Daniel Schneemann logo2D.Schneemann, CF.214.293.36311
Jose Ramirez logo3J.Ramirez, 3B.282.355.50028
Kyle Manzardo logo4K.Manzardo, 1B.241.322.47026
Bo Naylor logo5B.Naylor, C.187.280.36312
Gabriel Arias logo6G.Arias, SS.225.280.37011
Nolan Jones logo7N.Jones, RF.213.299.3085
CJ Kayfus logo8C.Kayfus, DH.212.278.4234
Brayan Rocchio logo9B.Rocchio, 2B.230.289.3284
Tigers Starting Lineup
Projected
PITCHERW-LERAWHIPK/9
Jack Flaherty logoRJ.Flaherty, P8-134.691.27910.57
HITTERSAVGOBPSLGHR
Parker Meadows logo1P.Meadows, CF.223.295.3444
Gleyber Torres logo2G.Torres, 2B.254.361.39416
Kerry Carpenter logo3K.Carpenter, DH.258.298.52126
Riley Greene logo4R.Greene, LF.265.319.50434
Spencer Torkelson logo5S.Torkelson, 1B.242.336.46129
Wenceel Perez logo6W.Perez, RF.259.320.45612
Colt Keith logo7C.Keith, 3B.254.330.41013
Dillon Dingler logo8D.Dingler, C.280.328.43413
Zach McKinstry logo9Z.McKinstry, SS.261.336.43911

Guardians vs. Tigers Odds Comparison

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Guardians at Tigers Team Totals

MatchupOverUnder
Guardians
79-71
N/A
N/A
Tigers
85-66
N/A
N/A