Reds vs. Brewers Odds & Betting Predictions - September 27, 2025

Reds at Brewers

12:10 am • FDSWI

Cincinnati Reds

0-2

3 - 1

Milwaukee Brewers

3-6

pitcher		team	era	w-l
Q.Priester			3.32	13-3
Z.Littell			3.58	8-8

MatchupOpenSpreadTotalMoneyline
Reds 0-2	+1.5	+1.5-154	o8-105	+141
Brewers 3-6	u7.5	-1.5+128	u8-115	-171

Saturday 12:10 a.m.

September 27, 2025

American Family FieldMilwaukee

Under 4.5 (F5)-115

0.5u

Don’t mind the u8 total but I also worry that Priester gets an abbreviated start and doesn’t get a full workload. Reds still playing for something but Brewers have division locked up. Targeting F5 under here hoping we get the best of Littell and Priester early on.

C.Yelich o1.5 Total Bases+110

$1.10

MIL -1-110

$1.10

Under 8-112

Under 8-105

0.95u

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Under 8.5-120

0.5u

Bet to 8 (-105)

Reds vs Brewers: Total Pick for Friday Night
Action Network Staff•
Sep 26, 2025 UTC

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No props found

MLB Public Betting

Brewers are 2-3 in their last 5 games.
Brewers are 2-3 in their last 5 games against the spread
Brewers are 48-33 in their road games against the spread
The totals have gone OVER in 1 of Brewers' last 5 games
The totals have gone OVER in 38 of Brewers' 81 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Brewers	88-74	40-41	48-33	43-53	44-21
Reds	82-78	40-39	42-39	29-43	53-34

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Brewers	77-80-5	38-40-3	39-40-2	50-44-2	27-35-3
Reds	58-91-11	26-45-8	32-46-3	20-47-5	37-44-6

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Brewers	97-65	52-29	45-36	59-37	37-28
Reds	83-79	44-35	38-43	39-33	43-44

date	opponent	score	spread	over/under	moneyline
Sep 24th	@SD	W 3-1	+1.5 W	U 7.5	MIL +122
Sep 24th	@SD	L 0-7	-1.5 L	U 8	SD -130
Sep 23rd	@SD	L 4-5	-1.5 L	O 7	SD -110
Sep 21st	@STL	L 1-5	-1.5 L	U 8.5	STL -132
Sep 20th	@STL	W 3-2	-1.5 L	U 8.5	MIL -145

Noelvi Marte
RF
Marte is day-to-day with side
Day-to-Day
Brandon Williamson
SP
Williamson is out for season with elbow
Out for Season
Graham Ashcraft
RP
Ashcraft is out with groin
Out
Chase Burns
SP
Burns is out with hip
Out
Julian Aguiar
SP
Aguiar is out for season with elbow
Out for Season
Rhett Lowder
SP
Lowder is out with elbow
Out

Easton McGee
SP
McGee is out with arm
Out
Garrett Mitchell
CF
Mitchell is out with oblique
Out
Coleman Crow
SP
Crow is out with elbow
Out

See more MLB Injuries

PITCHER	PC	IP	K	ER
RZ.Littell, P	85	4.2	3	1
RC.Phillips, P	16	1.1	3	0
RG.Ashcraft, P	9	1	1	0
RT.Santillan, P	10	1	1	0
RE.Pagan, P	12	1	1	0

HITTERS	H-AB	R	RBI
1T.Friedl, CF	2-3	0	0
2N.Marte, RF	0-4	0	0
3G.Lux, LF	2-4	2	0
3W.Benson, LF	0-0	0	0
4M.Andujar, DH	2-4	1	1
5E.De La Cruz, SS	1-4	0	0
6S.Steer, 1B	1-4	0	1
7T.Stephenson, C	1-3	0	1
8K.Hayes, 3B	0-3	0	0
9M.McLain, 2B	0-4	0	0

PITCHER	PC	IP	K	ER
RQ.Priester, P	87	5	4	3
RN.Mears, P	9	1	1	0
RT.Myers, P	36	3	2	0

HITTERS	H-AB	R	RBI
1C.Yelich, DH	1-4	1	0
2J.Chourio, CF	0-2	0	0
3B.Turang, 2B	1-4	0	1
4W.Contreras, C	0-4	0	0
5S.Frelick, RF	1-4	0	0
6A.Vaughn, 1B	0-3	0	0
7J.Bauers, LF	0-3	0	0
8A.Monasterio, 3B	0-3	0	0
9J.Ortiz, SS	0-3	0	0