The Chicago Cubs host the Arizona Diamondbacks on May 2, 2026. First pitch from Wrigley Field is scheduled for 2:20 p.m. EDT. The game will be broadcast on ARID.
The Cubs are favored by -160 on the moneyline and by -1.5 on the run line. The Diamondbacks are +135 on the moneyline and +1.5 on the run line. The total is set at 7.5 runs.
Find my MLB picks and Diamondbacks vs Cubs prediction below, as well as probable pitchers, weather report, and more.
Diamondbacks vs Cubs Prediction
- Diamondbacks vs Cubs Pick: Under 7.5
My Diamondbacks vs Cubs best bet is on the Under. Make sure to find the best odds by checking our live MLB odds page.
Diamondbacks vs Cubs Odds
| Diamondbacks Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+1.5 -162 | 7.5 -110o / -110u | +136 |
| Cubs Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-1.5 +134 | 7.5 -110o / -110u | -162 |
- Diamondbacks vs Cubs moneyline: Diamondbacks +135, Cubs -160
- Diamondbacks vs Cubs over/under: 7.5 (-110o / -110u)
- Diamondbacks vs Cubs spread: Cubs -1.5 (+134 ), Diamondbacks +1.5 (-161)
Diamondbacks vs Cubs Probable Pitchers
| Ryne Nelson (RHP, ARI) | Stat | Shota Imanaga (LHP, CHC) |
|---|---|---|
| 1-2 | W-L | 2-2 |
| -0.1 | fWAR (FanGraphs) | 1.0 |
| 7.71 / 5.23 | ERA / xERA | 3.15 / 2.93 |
| 5.59 / 4.78 | FIP / xFIP | 2.84 / 3.46 |
| 10.8% | K-BB% | 21.8% |
| 29.8% | GB% | 30.2% |
| .278 | BABIP | .217 |
| 105 | Stuff+ | 97 |
| 99 | Location+ | 109 |
Diamondbacks vs Cubs MLB Betting Preview
This game triggered one of our Action PRO betting systems, powered by Evan Abrams.
When the wind blows in at over five MPH, fly balls lose carry, and home run rates drop significantly.
This system targets unders in these conditions with totals between six and 11.
It’s a sharp weather-based angle that exploits environmental factors that are often underweighted in line-setting but heavily affect scoring outcomes.
Diamondbacks vs Cubs Pick, Betting Analysis
No stadium in baseball is more affected by wind direction than Wrigley Field. With the wind blowing in at close to 10 MPH and temperatures under 50 degrees, the run-scoring environment is going to be brutal — BallParkPal projects a -22% Runs factor behind a -36% Home Run factor.
The weather also helps these two starting pitchers, who are both fly-ball guys.
Ryne Nelson (29.8% GB) is due for tons of home-run regression (2.10 HR/9, 15% HR/FB), and he should get some on Saturday.
Meanwhile, Shota Imanaga (30.2% GB) is nearly unstoppable when the wind is blowing in at Wrigley.
Pick: Under 7.5
