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A’s vs Diamondbacks Prediction, Pick, MLB Odds for Tuesday, July 21

A’s vs Diamondbacks Prediction, Pick, MLB Odds for Tuesday, July 21 article feature image
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Jul 20, 2026; Phoenix, Arizona, USA; Arizona Diamondbacks shortstop Geraldo Perdomo (2) throws to first base as first baseman Ildemaro Vargas (6) looks on in the third inning against the Athletics at Chase Field. Mandatory Credit: Matt Kartozian-Imagn Images

The Arizona Diamondbacks host the Athletics on July 21, 2026. First pitch from Progressive Field is scheduled for 9:40 p.m. EDT. The game will be broadcast on NBCS-CA.

The Diamondbacks are favored by -134 on the moneyline and by -1.5 on the run line. The Athletics are +116 on the moneyline and +1.5 on the run line. The total is set at 9.5 runs.

Find my MLB picks and Athletics vs Diamondbacks prediction below, as well as probable pitchers, weather report, and more.


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Athletics vs Diamondbacks Prediction

  • Athletics vs Diamondbacks Pick: Under 9 (-105 or Better)

My Athletics vs Diamondbacks best bet is on the Under. Make sure to find the best odds by checking our live MLB odds page.


Athletics vs Diamondbacks Odds

Athletics Logo
Tuesday, Jul 21
9:40 p.m. ET
NBCS-CA
Diamondbacks Logo
Athletics Odds
SpreadTotalMoneyline
+1.5
-192
9.5
-106o / -114u
+116
Diamondbacks Odds
SpreadTotalMoneyline
-1.5
+158
9.5
-106o / -114u
-134
Odds via FanDuel. Get up-to-the-minute MLB odds here.
FanDuel Logo
  • Athletics vs Diamondbacks moneyline: Athletics +116, Diamondbacks -134
  • Athletics vs Diamondbacks over/under: 9.5 (-106 / -114)
  • Athletics vs Diamondbacks spread: Diamondbacks -1.5 (+158), Athletics +1.5 (-192)

Athletics vs Diamondbacks MLB Betting Preview

The Under 9.5 in this matchup is lighting up three of our Action PRO Signals:

Two of those can be attributed to our own Sean Zerillo, who projects just 8.5 runs for this matchup. If you'd like to learn more about this projection, I recommend checking out BARTOLO, our new PRO baseball betting tool giving our PRO subscribers access to all the data we use to project games each day.

Opening Pitch: Zerillo's MLB Projections for Tuesday via BARTOLO Image

Pick: Under 9 (-105 or Better)


Athletics vs Diamondbacks Weather


Get the latest coverage on MLB Weather.
Author Profile
About the Author

Tanner McGrath covers college basketball, college football and Major League Baseball at Action Network. He is a contributor to Payoff Pitch, Action Network’s Major League Baseball betting podcast. He's been working in the space for more than five years with past journalism experience in Canadian collegiate sports, finance and economics. He has an obsession with America East basketball, betting the Miami Marlins and sweating out home underdogs.

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