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Tigers vs Cubs Prediction, Pick, MLB Odds for Tuesday, July 21

Tigers vs Cubs Prediction, Pick, MLB Odds for Tuesday, July 21 article feature image
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Jun 22, 2026; Detroit, Michigan, USA; Detroit Tigers pitcher Framber Valdez (59) pitches in the first inning against the New York Yankees at Comerica Park. Mandatory Credit: Rick Osentoski-Imagn Images

The Chicago Cubs host the Detroit Tigers on July 21, 2026. First pitch from Wrigley Field is scheduled for 8:05 p.m. EDT. The game will be broadcast on DSN.

The Cubs are favored by -118 on the moneyline and by -1.5 on the run line. The Tigers are +100 on the moneyline and +1.5 on the run line. The total is set at 8 runs.

Find my MLB picks and Tigers vs Cubs prediction below, as well as probable pitchers, weather report, and more.


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Tigers vs Cubs Prediction

  • Tigers vs Cubs Pick: Under 7.5 (+100 or Better)

My Tigers vs Cubs best bet is on the Under. Make sure to find the best odds by checking our live MLB odds page.


Tigers vs Cubs Odds

Tigers Logo
Tuesday, Jul 21
8:05 p.m. ET
DSN
Cubs Logo
Tigers Odds
SpreadTotalMoneyline
-1.5
+164
8
-110o / -110u
+100
Cubs Odds
SpreadTotalMoneyline
+1.5
-200
8
-110o / -110u
-118
Odds via FanDuel. Get up-to-the-minute MLB odds here.
FanDuel Logo
  • Tigers vs Cubs moneyline: Tigers -100, Cubs -118
  • Tigers vs Cubs over/under: 8 (-110o / -110u)
  • Tigers vs Cubs spread: Cubs -1.5 (+164), Tigers +1.5 (-200)

Tigers vs Cubs Probable Pitchers

Framber Valdez (LHP, DET)StatDavid Peterson (LHP, CHC)
5-6W-L4-7
1.3fWAR (FanGraphs)0.6
4.10 / 4.22ERA / xERA6.45 / 5.36
4.10 / 4.22FIP / xFIP4.28 / 4.38
10.9%K-BB%8.6%
52.3%GB%47.2%
.292BABIP.338
102Stuff+88
99Location+99

Tigers vs Cubs MLB Betting Preview

Our own Sean Zerillo projects plenty of value on the Under in this game.

If you want to learn more about this matchup and our projection, I highly recommend checking out BARTOLO, our new PRO baseball betting tool giving PRO subscribers access to all the data we use to project MLB games every day.

Here's a sneak peek of BARTOLO's breakdown for Tigers-Cubs:

Opening Pitch: Zerillo's MLB Projections for Tuesday via BARTOLO Image

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Tigers vs Cubs Pick, Betting Analysis

The biggest handicapping factor in this matchup is the weather, as we’re expecting 17 MPH winds blowing in from left-center field.

As everyone should know by now, Wrigley Field is the most wind-receptive park in the league, and Unders are rather profitable in the North Side when the wind is blowing in. We have an Action PRO betting system dedicated to tracking this phenomenon.

MLB Icon
Wrigley Field Unders (PRO)
the average wind speed is between 5 and 40 mph
the wind direction is In or From Left or Left to Right or From Right or Right To Left
the game is played during the Regular season
the opening total is between 8 and 13
the home team is Chicago Cubs
betting on the Under
$8,638
WON
315-207-30
RECORD
60%
WIN%

Pick: Under 7.5 (+100 or Better)


Tigers vs Cubs Weather


Get the latest coverage on MLB Weather.
Author Profile
About the Author

Tanner McGrath covers college basketball, college football and Major League Baseball at Action Network. He is a contributor to Payoff Pitch, Action Network’s Major League Baseball betting podcast. He's been working in the space for more than five years with past journalism experience in Canadian collegiate sports, finance and economics. He has an obsession with America East basketball, betting the Miami Marlins and sweating out home underdogs.

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