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Siena vs. Duke Odds & Betting Predictions - March 19, 2026

Siena at Duke

6:50 pm • CBS

Siena Saints

23-11
@

Duke Blue Devils

32-2

Siena at Duke Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Siena
23-11
+26.5
+28.5-110
o135.5-115
+3300
Duke
32-2
u136.5
-28.5-110
u135.5-105
-10000
location pinThursday 6:50 p.m.
March 19, 2026
Bon Secours Wellness ArenaGreenville
Siena vs. Duke Expert Picks
Royals Props
Royals Props
Last 30d: 23-28-0 (-9.2u)
C.Boozer o22.5 Pts-106
1.06u
Stuck 🚨
Stuck 🚨
Last 30d: 52-62-4 (-0.1u)
SIE +29.5-110
0.4u
Will have this written up but this is a huge number for a limited possession game and not sure Duke will rush anybody back for R1. Just gotta defend without fouling since Siena has absolutely zero depth now. If so, can keep this within 25. Siena lives in midrange which is where Duke wants you and Coyle has found his shot again recently. Massive backdoor shot if needed too
Babs .
Babs .
Last 30d: 76-69-0 (-1.5u)
SIE +29.5-110
1u
Duck
Duck
Last 30d: 78-87-0 (-10.9u)
Under 136.5-110
0.5u

Siena vs. Duke Previews & Analysis

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    Action Network March Madness Betting Primer

    Evan Abrams•
    Mar 16, 2026 UTC
  • McGrath's Projected Scores for Every NCAA Tournament First-Round Matchup article feature image

    McGrath's Projected Scores for Every NCAA Tournament First-Round Matchup

    Tanner McGrath•
    Mar 16, 2026 UTC
  • Why Midwest Region is Ripe for Upsets article feature image

    Why Midwest Region is Ripe for Upsets

    Jordan Mann•
    Mar 16, 2026 UTC
  • Duke vs. Siena Opening Odds article feature image

    Duke vs. Siena Opening Odds

    Action Network Staff•
    Mar 15, 2026 UTC
See more NCAAB Coverage Right Arrow

Prop Odds Comparison

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Line Movement Tracker

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Siena vs. Duke Public Betting Percentages

Away Logo

Siena

Public

Home Logo

Duke

77%

Bets%

23%

Money%

NCAAB Public Betting Right Arrow

Betting Trends

  • Duke are 5-0 in their last 5 games.
  • Duke are 2-3 in their last 5 games against the spread
  • Duke are 8-3 in their road games against the spread
  • The totals have gone OVER in 3 of Duke' last 5 games
  • The totals have gone OVER in 8 of Duke' 23 last games at home

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Duke		19-1511-128-315-131-0
Siena		20-149-711-716-124-2

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Duke		12-228-154-710-180-1
Siena		11-234-127-118-203-3

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Duke		32-2N/AN/A26-21-0
Siena		23-11N/AN/A21-72-4

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Mar 15thUVAW 74-70-6.5 LO 139.5DUKE -295
Mar 14thCLEMW 73-61-10.5 WU 134.5DUKE -610
Mar 12thFSUW 80-79-17 LO 150.5DUKE -2800
Mar 7thUNCW 76-61-18.5 LU 147.5DUKE -3600
Mar 3rd@NCSTW 93-64-9.5 WO 150.5DUKE -500

Duke vs. Siena Injury Updates

Duke Injuries

  • Ifeanyi Ufochukwu
    C

    Ufochukwu is out with undisclosed

    Out

  • Caleb Foster
    G

    Foster is out with foot

    Out

  • Patrick Ngongba
    C

    Ngongba is probable with undisclosed

    Probable

Siena Injuries

  • Reid Ducharme
    G

    Ducharme is out with shoulder

    Out

  • Tasman Goodrick
    F

    Goodrick is out for season with knee

    Out for Season

  • Antonio Chandler
    F

    Chandler is out with undisclosed

    Out

  • Owen Schlager
    G

    Schlager is out with ribs

    Out

See more NCAAB Injuries Right Arrow
Team Stats

25-55 (45%)
Field Goals
28-58 (48%)
14-18 (78%)
Free Throws
15-22 (68%)
5-17 (29%)
3P
9-25 (36%)
31.03
Rebounds
37.41
13.4
Assists
16.9
9.68
Turnovers
10.18
5.79
Steals
7.79
3.12
Blocks
3.26
13.74
Fouls
15.71

Siena vs. Duke Odds Comparison

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Siena at Duke Team Totals

MatchupOverUnder
Siena
23-11
N/A
N/A
Duke
32-2
N/A
N/A