College Football Odds for Clemson vs Duke
| Clemson Odds | -12.5 |
| Duke Odds | +12.5 |
| Over/Under | 54.5 |
| Date | Monday, Sept. 4 |
| Time | 8 p.m. ET |
| Channel | ESPN |
*College football odds as of Monday afternoon
The final game of college football's Week 1 slate takes place on Monday night with the Clemson Tigers visiting the Duke Blue Devils.
The latest college football odds have Clemson as a 13-point favorite against Duke and the over/under set at 55.5, but it's the total that's drawing attention from the market's biggest bettors.
With this in mind, let's dig into the Action Network's PRO betting tools to identify the college football over/under pick that the pros are making for Clemson vs. Duke on Monday night.
