The New Mexico State Aggies take on the Tennessee Volunteers in Knoxville, Tennessee. Kickoff is set for 4:15 p.m. EST on SEC Network.
Tennessee is favored by 39.5 points on the spread. The total is set at 61.5 points.
Here’s my New Mexico State vs. Tennessee prediction and college football picks for Saturday, November 15, 2025.
New Mexico State vs Tennessee Prediction
- New Mexico State vs. Tennessee Pick: Tennessee -39.5 (-110, bet365)
My Tennessee vs. New Mexico State best bet is on the Vols to cover the big spread. Find the best line available on our live NCAAF odds page.
New Mexico State vs Tennessee Odds
| New Mexico State Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+39.5 -110 | 61.5 -110o / -110u | |
| Tennessee Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-39.5 -110 | 61.5 -110o / -110u | |
- New Mexico State vs Tennessee point spread: Tennessee -39.5 (-110), New Mexico State +39.5 (-110)
- New Mexico State vs Tennessee over/under: 61.5 (-110o / -110u)
New Mexico State vs Tennessee Preview
Historically, Tennessee drops the hammer on lesser opponents in spots like this.
This is a complete lay-down-and-die spot for New Mexico State. The Aggies’ Bowl hopes have evaporated. They’ve lost four games in a row. They’ve allowed over 400 yards of total offense in each of the past four weeks.
Meanwhile, the Volunteers are off their Bye week, and will want to get some reps for the starters early in this one before letting the second-stringers mop things up, hopefully staying healthy for the Florida game next week.
Let’s look at how Josh Heupel has handled these late-season spots against inferior competition:
- 2024: 56-0 over UTEP (laying 41.5)
- 2023: 59-3 over UConn
- 2022: 66-24 over UT Martin
- 2021: 60-14 over South Alabama
Tennessee won’t sleepwalk through this game, as it hasn’t in this spot over the past four seasons.
Pick: Tennessee -39.5 (-110, bet365)
