The Virginia Cavaliers take on the Duke Blue Devils in Durham, North Carolina. Kickoff is set for 3:30 p.m. ET on ESPN2.
Duke is favored by 4.5 points on the spread with a moneyline of -200. The total is set at 58.5 points.
Here’s my Virginia vs. Duke prediction and college football picks for Saturday, November 15.
Virginia Cavaliers vs Duke Blue Devils Prediction, Picks
- Virginia vs. Duke Pick: Over 58.5 or Better
My Duke vs. Virginia best bet is on the Cavaliers to cover and the Over. Find the best line available on our live NCAAF odds page.
Virginia vs Duke Odds, Line
| Virginia Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+5 -113 | 59.5 -108o / -114u | +148 |
| Duke Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-5 -112 | 59.5 -108o / -114u | -195 |
- Virginia vs Duke Spread: Duke -5, Virginia +5
- Virginia vs Duke Over/Under: 59.5 Points
- Virginia vs Duke Moneyline: Virginia ML +148, Duke ML -195
Virginia vs Duke Pick, Betting Preview
Duke’s defense is horrific.
The Blue Devils rank 117th or worse nationally in EPA per pass allowed, PFF’s Coverage grades, and Defensive Finishing Drives.
With J’Mari Taylor and Harrison Waylee returning, I also expect Virginia to break plenty of explosive rushes. Those two have a combined 24 explosive runs this season, and Waylee is averaging over four yards after contact per rush.
I expect Virginia to be in scoring position all night.
Meanwhile, Darian Mensah has been on a heater. Since Week 4, he’s thrown for 16 touchdowns with just two interceptions.
He’ll see Cover One and Quarters coverage coming from the Virginia secondary, and Mensah is explosive against both.
So, I love the Over.
Pick: Over 58.5 or Better
