The Green Bay Packers (3-1-1) and Arizona Cardinals (2-4) will face off in Week 7 of the NFL season on Sunday afternoon. Kickoff is set for in 4:25 p.m. ET from State Farm Stadium in Glendale, Ariz. The game will broadcast live on FOX.
The Packers are 7-point favorites over the Cardinals on the spread (Packers -7; -115), with the over/under set at 44.5 (-108o / -112u). Green Bay is a -380 favorite to win outright on the moneyline, while Arizona is +300 to pull off the upset.
Let's get into my Packers vs Cardinals predictions for Sunday, October 19, plus the latest odds, NFL betting trends, viewing information and more.
Packers vs Cardinals Prediction, Picks
- Packers vs Cardinals pick: Cardinals +7 (-110)
My Cardinals vs. Packers best bet is on Arizona to cover the spread. Find the best odds by checking our live NFL odds page.
Packers vs Cardinals Odds
| Packers Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-7 -115 | 44.5 -108o / -112u | -380 |
| Cardinals Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+7 -105 | 44.5 -108o / -112u | +300 |
Packers vs Cardinals Preview, Prediction
The Packers are considered a true Super Bowl contender, but the market may still be overrating them.
Outside of an offensive explosion against a highly vulnerable Cowboys defense, Green Bay has a season high of 27 points scored and has failed to cover on the road in both opportunities.
The Cardinals defense is a respectable 13th in DVOA and yards per play allowed, but what I like most about them is their ability to limit explosive plays. They have yet to allow a single touchdown from outside of the red zone.
The Packers offense, which is just league average in pace, will have to generate points by sustaining time consuming drives, which just makes it more difficult to win with margin.
Jacoby Brissett stepped in for an injured Kyler Murray in Week 6 and played extremely well. Brissett didn’t have a single turnover-worthy throw while accounting for 320 passing yards.
For context, Murray has reached that passing yardage total in a single game just once since the middle of the 2022 regular season.
Even more interesting than the numbers was the change in offensive approach for the Cardinals. Offensive coordinator Drew Petzing opted to have Brissett play from under center at twice the rate he has asked Murray to so far this season.
Furthermore, Petzing used a heavy dose of play-action pass and it was highly effective, averaging 8.1 yards per attempt.
The play-action dropbacks generated production despite running backs Bam Knight and Michael Carter combining to average 3.4 yards per carry on 20 rushes — once again solidifying the fact that you do not need to run the ball effectively to have play-action give a boost to your passing attack.
This is important heading into the Cardinals matchup with the Packers’ defense considering this will be a much tougher test than what an injury-riddled Colts’ secondary provided last week.
Green Bay is second in the league in yards per play allowed and it boasts the top pass defense in football in yards per pass attempt.
My expectation is that Brissett will garner another start, and that Marvin Harrison Jr. should be able to clear concussion protocol by Sunday as he worked without a non-contact jersey at Friday’s practice. Simply put, the offensive circumstance for the Cardinals is going to sway my handicap of this game.
If I am correct in my assessment of these two players, I believe the Arizona offense can execute regularly enough to sustain drives with Harrison drawing the attention needed to open things up for Trey McBride.
McBride was the focal point of the play-action passing attack Petzing implemented, with more than 40% of those passes going to the tight end. The Packers rank 26th in yards per game allowed to the tight end position, which makes it an area Arizona can exploit on Sunday.
Packers vs Cardinals Best Bet, Spread Pick
The Packers have struggled to cover on the road as favorites under head coach Matt LaFleur.
Home underdogs against LaFleur are 16-10 against the spread, covering at a 61.5% rate.
More specifically, when that underdog is catching more than a field goal, they are 13-6 ATS (68.4%).
In the Jordan Love era under LaFleur, home 'dogs of more than a field goal are a perfect 6-0 against the number when facing the Packers.
Packers vs Cardinals Best Bet
- Cardinals +7 (-110)
Packers vs Cardinals Betting Trends
Packers vs Cardinals Viewing Info: Channel, Start Time, Streaming
| Location: | State Farm Stadium in Glendale, Ariz. |
| Date: | Sunday, Oct. 19 |
| Time: | 4:25 p.m. ET |
| TV / Streaming Options: | FOX |
For the latest on NFL injuries, be sure to check out our NFL Injury Report page.
Packers vs Cardinals Weather
