Cubs vs. Reds Odds & Betting Predictions - May 23, 2025

Cubs at Reds

10:40 pm • MARQ
13 - 6
Starting Pitchers
pitcherteameraw-l
Hunter Greene logoH.GreeneCincinnati Reds logo2.544-2
Matthew Boyd logoM.BoydChicago Cubs logo3.424-2

Cubs at Reds Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Cubs
31-21
-1.5
-1.5+147
o8.5-105
-116
Reds
26-27
u8.5
+1.5-175
u8.5-120
-103
location pinFriday 10:40 p.m.
May 23, 2025
Great American Ball ParkCincinnati
Cubs vs. Reds Expert Picks
Allan Lem
Allan Lem
Last 30d: 31-37-0 (-3.2u)
M.Boyd u5.5 Ks+115
1u
Tailing @The_Oddsmaker
Sean Koerner
Sean Koerner
Last 30d: 13-16-0 (-2.4u)
M.Boyd u5.5 Ks+115
1.15u
Boyd has cleared this line in 4 straight, but that’s largely due to an easier schedule — and this sets up as a sharp sell-high spot. The Reds rank 4th in K% on the season, but today’s lineup projects closer to league average. Boyd’s 24.8% K rate has outpaced his expected mark (21.6% in my model), so some regression looks likely. His best strikeout pitch is the slider (35%+ whiff rate), and while the Reds have struggled badly against sliders (worst whiff rate in MLB), they’re right around league average vs. fastballs, changeups, and curveballs — which is notable because Boyd leans on that mix against right-handed hitters, and the Reds are sending up 8 of them today. His most likely K range is 4–6, and with the under, we win on 2 of those 3 outcomes. I project this closer to -140, making +115 a strong value.
Grant Neiffer
Grant Neiffer
Last 30d: 32-130-5 (+18.8u)
K.Tucker o0.5 HR+380
0.5u
S.Suzuki o0.5 HR+425
2.13u
Cam Is Money
Cam Is Money
Last 30d: 124-151-5 (-25.4u)
CHC -105 (F5)
1u
Austin Pendergrass
Austin Pendergrass
Last 30d: 94-120-3 (-18.9u)
Under 0.5 (1st Inn)-150
0.5u
Sean Zerillo
Sean Zerillo
Last 30d: 136-158-7 (-10.8u)
Under 8.5-104
0.52u
Bet to -115
The Propfessor
The Propfessor
Last 30d: 26-37-0 (-14.7u)
M.Boyd o17.5 Outs-130
1.3u

Cubs vs. Reds Previews & Analysis

  • Cubs vs Reds: +180 SGP for Friday article feature image

    Cubs vs Reds: +180 SGP for Friday

    Chilly Bets
    May 23, 2025 UTC
  • 5 Home Run Prop Bets & Parlay for Friday article feature image

    5 Home Run Prop Bets & Parlay for Friday

    Grant Neiffer
    May 23, 2025 UTC
See more MLB Coverage Right Arrow

Prop Odds Comparison

Right Arrow
Right Arrow

No props found

Line Movement Tracker

Right Arrow
Right Arrow

Cubs vs. Reds Public Betting Percentages

Away Logo

Cubs

Public

69%

Bets%

31%

Money%

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Reds
28-2515-1213-1312-1216-12
Cubs
27-2513-1214-1318-159-10

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Reds
20-31-210-16-110-15-15-17-214-14
Cubs
31-18-316-8-115-10-219-12-212-6-1

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Reds
26-2714-1312-1413-1113-15
Cubs
31-2115-1016-1122-119-10

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
May 21st@PITL 1-3-1.5 LU 8PIT -128
May 20th@PITL 0-1-1.5 LU 8PIT -145
May 19th@PITW 7-1-1.5 WU 8CIN -116
May 18thCLEW 3-1-1.5 WU 9CIN -135
May 17thCLEW 4-1+1.5 WU 10CIN -105

Cubs vs. Reds Injury Updates

Cubs Injuries

  • Drew Pomeranz
    RP

    Pomeranz is out with elbow

    Out

  • Justin Steele
    SP

    Steele is out for season with elbow

    Out for Season

Reds Injuries

  • Jake Fraley
    RF

    Fraley is out with calf

    Out

  • Noelvi Marte
    3B

    Marte is day-to-day with side

    Day-to-Day

  • Brandon Williamson
    SP

    Williamson is out for season with elbow

    Out for Season

  • Julian Aguiar
    SP

    Aguiar is out for season with elbow

    Out for Season

  • Rhett Lowder
    SP

    Lowder is out with elbow

    Out

  • Carson Spiers
    RP

    Spiers is out with shoulder

    Out

Cubs vs. Reds Box Score
Cubs Player Stats
Projected
PITCHERPCIPKER
Matthew Boyd logoLM.Boyd, P93434
Julian Merryweather logoRJ.Merryweather, P320.202
Chris Flexen logoRC.Flexen, P141.100
Brad Keller logoRB.Keller, P17110
Drew Pomeranz logoLD.Pomeranz, P15110
Ryan Pressly logoRR.Pressly, P16110
HITTERSH-ABRHRRBI
Ian Happ logo1I.Happ, LF1-4200
Kyle Tucker logo2K.Tucker, DH1-5102
Seiya Suzuki logo3S.Suzuki, RF3-5313
Pete Crow-Armstrong logo4P.Crow-Armstrong, CF3-5226
Carson Kelly logo5C.Kelly, C1-4100
Michael Busch logo6M.Busch, 1B0-4000
Dansby Swanson logo7D.Swanson, SS1-4112
Nico Hoerner logo8N.Hoerner, 2B3-5200
Matt Shaw logo9M.Shaw, 3B0-5100
Reds Player Stats
Projected
PITCHERPCIPKER
Hunter Greene logoRH.Greene, P83422
Scott Barlow logoRS.Barlow, P181.130
Taylor Rogers logoLT.Rogers, P100.200
Ian Gibaut logoRI.Gibaut, P120.103
Tony Santillan logoRT.Santillan, P17003
Brent Suter logoLB.Suter, P351.223
Luis Mey logoRL.Mey, P23102
HITTERSH-ABRHRRBI
TJ Friedl logo1T.Friedl, CF2-5101
Santiago Espinal logo2S.Espinal, 3B1-4100
Elly De La Cruz logo3E.De La Cruz, SS1-5100
Austin Hays logo4A.Hays, LF2-5101
Spencer Steer logo5S.Steer, 1B3-5101
Tyler Stephenson logo6T.Stephenson, DH1-4101
Jose Trevino logo7J.Trevino, C0-2000
Gavin Lux logo7G.Lux, PH0-0000
Austin Wynns logo7A.Wynns, C1-1000
Connor Joe logo8C.Joe, RF1-2000
Will Benson logo8W.Benson, PH0-2000
Will Benson logo8W.Benson, RF0-2000
Matt McLain logo9M.McLain, 2B1-4000

Cubs vs. Reds Odds Comparison

Right Arrow

Could not load odds

Cubs at Reds Team Totals

MatchupOverUnder
Cubs
31-21
o4.5+114
u4.5-145
Reds
26-27
o3.5-138
u3.5+108