Mariners vs. Astros Odds & Betting Predictions - September 20, 2025

Mariners at Astros

12:10 am • SCHN

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Seattle Mariners

@

Houston Astros

pitcher		team	era	w-l
H.Brown			0.00	0-0
B.Woo			0.00	0-0

MatchupOpenSpreadTotalMoneyline
Mariners 83-69	-1.5	-1.5+168	o7.5+100	-105
Astros 84-69	u7.5	+1.5-205	u7.5-120	-113

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Saturday 12:10 a.m.

September 20, 2025

Daikin ParkHouston

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86°Fahrenheit

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0%Rain

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8Wind

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MLB Public Betting

Astros are 4-1 in their last 5 games.
Astros are 4-1 in their last 5 games against the spread
Astros are 42-33 in their road games against the spread
The totals have gone OVER in 3 of Astros' last 5 games
The totals have gone OVER in 34 of Astros' 78 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Astros	79-74	37-41	42-33	40-57	39-15
Mariners	63-89	34-41	29-48	39-66	23-21

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Astros	69-77-7	34-42-2	35-35-5	44-51-2	23-26-5
Mariners	83-63-6	38-32-5	45-31-1	53-46-6	28-16

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Astros	84-69	46-32	38-37	53-44	31-23
Mariners	83-69	48-27	35-42	60-45	21-23

date	opponent	score	spread	over/under	moneyline
Sep 18th	TEX	W 5-2	+1.5 W	U 7.5	HOU +122
Sep 17th	TEX	W 6-5	+1.5 W	O 7.5	HOU +100
Sep 16th	TEX	W 6-3	-1.5 W	O 8.5	HOU -132
Sep 14th	@ATL	L 3-8	-1.5 L	O 9	ATL -137
Sep 13th	@ATL	W 6-2	-1.5 W	U 8.5	HOU -139

Pedro Leon
RF
Leon is out with knee
Out
Hayden Wesneski
RP
Wesneski is out with elbow
Out

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MatchupOverUnder
Mariners 83-69	N/A	N/A
Astros 84-69	N/A	N/A