Orioles vs. Guardians Odds & Betting Predictions - July 23, 2025

Orioles at Guardians

10:40 pm • CLEG
2 - 3
Starting Pitchers
pitcherteameraw-l
Slade Cecconi logoS.CecconiCleveland Guardians logo3.765-4
Zach Eflin logoZ.EflinBaltimore Orioles logo5.786-5

Orioles at Guardians Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Orioles
45-57
-1.5
+1.5-191
o8.5-117
+110
Guardians
51-51
u8.5
-1.5+155
u8.5-103
-130
location pinWednesday 10:40 p.m.
July 23, 2025
Progressive FieldCleveland
Orioles vs. Guardians Expert Picks
Boomer Betz
Boomer Betz
Last 30d: 239-240-4 (+20.3u)
BAL +144 (Live)
1u
Sir Lockselot
Sir Lockselot
Last 30d: 33-52-0 (+0.3u)
BAL +110
2u
🔑 Orioles ML +110 (FanDuel) 2u Sharp fade angle: 78% of bets & 82% of ML money showing on Guardians, yet line movement has held steady and even ticked toward Baltimore in spots – a classic sign of sharp money backing the O’s. Pitching edge: Zach Eflin’s overall ERA (5.95) hides the fact that he’s posted a much stronger 3.41 ERA over his last 3 starts. Baltimore’s lineup has been heating up with Gunnar Henderson and Ryan O’Hearn combining for 4 HRs over the last week. Contrarian underdog with recent offensive surge and positive steam signals.
Al’s Analytics
Al’s Analytics
Last 30d: 46-37-0 (+6.3u)
Under 8.5-105
0.95u
95% of the money is on the Over…. We have some beautiful systems that aline to help us fade the public here Bad Teams Won Last Game and Game 3 56-15-2 (78.87%) 49.19% ROI 42-11 (79.2%) in 2025 Orioles Road Dog Series Closer 49-24-6 (67.1%) 26.01% ROI 13-3 (81.2%) in 2025 Guardians Home Under’s After Win After ASB 72-37-3 (66.1%) 25.41% ROI
Scott Rickenbach
Scott Rickenbach
Last 30d: 68-73-3 (-18.4u)
Over 8.5-118
1u
Lines at Lunch
Lines at Lunch
Last 30d: 46-55-6 (-14.5u)
G.Henderson o1.5 Total Bases+100
1u
Ryan Sura
Ryan Sura
Last 30d: 41-50-7 (+20.5u)
G.Henderson o1.5 Total Bases+100
1u
Sandy Plashkes
Sandy Plashkes
Last 30d: 83-77-2 (+10.6u)
G.Henderson o1.5 Total Bases+100
1u
Lines at Lunch
Lines at Lunch
Last 30d: 46-55-6 (-14.5u)
BAL +108
0.93u
Jim Sannes
Jim Sannes
Last 30d: 19-41-0 (-8.3u)
S.Cecconi o5.5 Ks+112
1u
Increased strikeout rate this year is paired with an increase in his swinging-strike rate, and the sample is up to 11 starts. Buying in enough to see value in the over.
Brian Bitler
Brian Bitler
Last 30d: 58-66-2 (-13.3u)
BAL +110
3u
CeeJ Sports
CeeJ Sports
Last 30d: 23-18-0 (+1.7u)
CLE -124
0.81u
Eflin is on the mound for the Orioles, and he has struggled vs lefties, which is a problem for him with this CLE lineup stacked with lefties. The CLE offense has come alive since the All-Star break, scoring 40 runs in their last 5 games. They are 4-1 since the break and have taken the first 2 games of this series, scoring 16 runs. Efflin's last 3 starts, the Orioles have lost by a combined 27-4. In those 3 games, he gave up 7,6,4 earned runs and allowed 12,10, and 5 hits. AKA, he is trash. Break out the brooms in Cleveland.

Orioles vs. Guardians Previews & Analysis

  • Orioles vs. Guardians: System Points to Under article feature image

    Orioles vs. Guardians: System Points to Under

    Action Network Staff
    Jul 23, 2025 UTC
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Prop Odds Comparison

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Line Movement Tracker

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Orioles vs. Guardians Public Betting Percentages

Away Logo

Orioles

Public

25%

Bets%

75%

Money%

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Guardians
53-4924-2629-2321-2032-28
Orioles
43-5918-2925-3016-3225-27

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Guardians
44-54-424-25-120-29-321-2023-33-4
Orioles
43-56-324-21-219-35-123-23-219-32-1

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Guardians
51-5125-2526-2626-1525-35
Orioles
45-5722-2523-3221-2722-30

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Jul 22ndBALW 6-3-1.5 WO 8CLE -161
Jul 21stBALW 10-5-1.5 WO 8.5CLE -143
Jul 20thATHW 8-2+1.5 WO 7.5CLE -106
Jul 19thATHL 2-8-1.5 LO 9ATH -134
Jul 18thATHW 8-6-1.5 WO 8CLE -134

Guardians vs. Orioles Injury Updates

Guardians Injuries

  • Gabriel Arias
    SS

    Arias is out with leg

    Out

  • Ben Lively
    SP

    Lively is out with elbow

    Out

  • Shane Bieber
    SP

    Bieber is out with elbow

    Out

  • John Means
    SP

    Means is out with elbow

    Out

Orioles Injuries

  • Albert Suarez
    RP

    Suarez is out with shoulder

    Out

  • Jorge Mateo
    SS

    Mateo is out with hamstring

    Out

  • Kyle Bradish
    SP

    Bradish is out with elbow

    Out

  • Grayson Rodriguez
    SP

    Rodriguez is out with elbow

    Out

  • Tyler Wells
    SP

    Wells is out with elbow

    Out

  • Adley Rutschman
    C

    Rutschman is out with oblique

    Out

  • Cade Povich
    SP

    Povich is out with hip

    Out

Orioles vs. Guardians Box Score
Orioles Player Stats
Projected
PITCHERPCIPKER
Zach Eflin logoRZ.Eflin, P84552
Andrew Kittredge logoRA.Kittredge, P10100
Yennier Cano logoRY.Cano, P13100
Colin Selby logoRC.Selby, P23111
HITTERSH-ABRHRRBI
Jackson Holliday logo1J.Holliday, DH1-3111
Jordan Westburg logo2J.Westburg, 2B1-4100
Gunnar Henderson logo3G.Henderson, SS0-4000
Ryan O'Hearn logo4R.O'Hearn, 1B1-3001
Ramon Laureano logo5R.Laureano, RF1-4000
Colton Cowser logo6C.Cowser, LF0-3000
Ramon Urias logo7R.Urias, 3B0-1000
Cedric Mullins logo8C.Mullins, CF1-3000
Jacob Stallings logo9J.Stallings, C0-2000
Dylan Carlson logo9D.Carlson, PH0-1000
Alex Jackson logo9A.Jackson, C0-0000
Guardians Player Stats
Projected
PITCHERPCIPKER
Slade Cecconi logoRS.Cecconi, P85622
Nic Enright logoRN.Enright, P12110
Hunter Gaddis logoRH.Gaddis, P15110
Emmanuel Clase logoRE.Clase, P12120
HITTERSH-ABRHRRBI
Steven Kwan logo1S.Kwan, LF1-3101
Angel Martinez logo2A.Martinez, CF0-3000
Jose Ramirez logo3J.Ramirez, 3B1-4100
Kyle Manzardo logo4K.Manzardo, DH1-3002
Carlos Santana logo5C.Santana, 1B0-3000
Nolan Jones logo6N.Jones, RF0-3000
Daniel Schneemann logo7D.Schneemann, 2B0-3000
Brayan Rocchio logo8B.Rocchio, SS0-3000
Bo Naylor logo9B.Naylor, C1-3100
Austin Hedges logo9A.Hedges, C0-0000

Orioles vs. Guardians Odds Comparison

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Orioles at Guardians Team Totals

MatchupOverUnder
Orioles
45-57
o3.5-150
u3.5+115
Guardians
51-51
o4.5+104
u4.5-132