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Twins vs. Guardians Odds & Betting Predictions - April 28, 2025

Twins at Guardians

10:10 pm • MNNT

Minnesota Twins

34-27
11
11 - 1

Cleveland Guardians

33-27
1
Starting Pitchers
pitcherteameraw-l
Gavin Williams logoG.WilliamsCleveland Guardians logo3.795-3
Bailey Ober logoB.OberMinnesota Twins logo3.484-1

Twins at Guardians Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Twins
34-27
+1.5
+1.5-198
o8-117
+105
Guardians
33-27
u8
-1.5+167
u8-105
-125
location pinMonday 10:10 p.m.
April 28, 2025
Progressive FieldCleveland
Twins vs. Guardians Expert Picks
The Degenerate
The Degenerate
Last 30d: 19-28-0 (-0.4u)
MIN +0.5 (F5)-140
0.54u
Picks Office
Picks Office
Last 30d: 79-75-0 (+3.1u)
CLE -120
1u
Twins can't win on the road – just 3-10 away this season, batting an ugly .188 with 2.92 R/9. Guardians strong at home – 8-4 record, offense jumps to 4.14 R/9. Gavin Williams (2-0, 2.38 ERA home) thrives at Progressive Field, Twins have lost 7 of last 8 here. Bailey Ober’s road nightmares – 9.35 ERA, 1.96 WHIP in 8.2 IP away. Guardians bullpen edge – 2.89 ERA vs Twins’ 3.65 bullpen ERA season-long. Cleveland better vs RHP – .238 AVG compared to Twins’ .232. Guardians’ offense has enough pop to expose Ober's road splits. Twins' brutal trend: 20 losses in last 26 road games. Home momentum, bullpen depth, starting pitching tilt to CLE.
Top Shelf Action 🥃
Top Shelf Action 🥃
Last 30d: 139-165-3 (+1.9u)
E.Julien o1.5 Total Bases+185
1.11u
B.Naylor o0.5 Doubles+600
0.2u
K.Manzardo o0.5 Doubles+500
0.2u
Jim Sannes
Jim Sannes
Last 30d: 34-51-0 (+1.1u)
G.Williams u5.5 Ks-102
0.98u
Have him projected for 5.45 strikeouts. Pitchers in that range for me have gone under 5.5 at a rate around 60%.
Top Shelf Action 🥃
Top Shelf Action 🥃
Last 30d: 139-165-3 (+1.9u)
C.Correa o1.5 RBI+650
0.2u
C.Correa o1.5 Hits+275
1.38u
Greg DiNardo
Greg DiNardo
Last 30d: 39-55-0 (-20.0u)
CLE -130
1.3u
Capper Central
Capper Central
Last 30d: 118-89-2 (+16.2u)
CLE PK-107
1.07u
Moneyline Hacks
Moneyline Hacks
Last 30d: 100-64-2 (+60.5u)
CLE -120
1u
🔥All Access VIP Picks⬇️ https://linktr.ee/moneylinehacks Get VIP Pick Texts to Your Phone Get our best plays via SMS and unlock full access to the MoneylineHacks Discord community. 🚨3000+ members strong. 📈22-11 on Tennis PODs the last 4 weeks. Choose the option that works best for you⬇️: • VIP Picks via Winible (SMS Text Access) • VIP Picks via DubClub 🚨Use promo code HACKS60 for 60% OFF your subscription.
Sean Zerillo
Sean Zerillo
Last 30d: 138-142-6 (-2.6u)
CLE -110
0.55u
Bet to -121

Twins vs. Guardians Previews & Analysis

  • Twins vs. Guardians: The Clear Side to Bet article feature image

    Twins vs. Guardians: The Clear Side to Bet

    John Feltman•
    Apr 28, 2025 UTC
  • Zerillo's Monday MLB Predictions article feature image

    Zerillo's Monday MLB Predictions

    Sean Zerillo•
    Apr 28, 2025 UTC
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Prop Odds Comparison

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Line Movement Tracker

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Twins vs. Guardians Public Betting Percentages

Away Logo

Twins

Public

Home Logo

Guardians

25%

Bets%

75%

Money%

MLB Public Betting Right Arrow

Betting Trends

  • Guardians are 3-2 in their last 5 games.
  • Guardians are 4-1 in their last 5 games against the spread
  • Guardians are 16-16 in their road games against the spread
  • The totals have gone OVER in 1 of Guardians' last 5 games
  • The totals have gone OVER in 12 of Guardians' 28 last games at home

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Guardians		30-3014-1416-1611-1119-18
Twins		36-2517-919-1623-1613-9

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Guardians		26-31-312-15-114-16-212-1014-20-3
Twins		21-36-48-17-113-19-314-23-27-13-2

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Guardians		33-2717-1116-1615-718-19
Twins		34-2718-816-1924-1510-12

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Apr 27thBOSL 3-13+1.5 LO 7.5BOS +100
Apr 26thBOSL 3-7+1.5 LO 7.5BOS +102
Apr 26thBOSW 5-4+1.5 WO 7.5CLE -105
Apr 23rdNYYL 1-5+1.5 LU 8.5NYY +144
Apr 22ndNYYW 3-2+1.5 WU 8.5CLE -120

Guardians vs. Twins Injury Updates

Guardians Injuries

  • Ben Lively
    SP

    Lively is out with elbow

    Out

  • Shane Bieber
    SP

    Bieber is out with elbow

    Out

  • John Means
    SP

    Means is out with elbow

    Out

Twins Injuries

    See more MLB Injuries Right Arrow
    Twins vs. Guardians Box Score
    Twins Player Stats
    Projected
    PITCHERPCIPKER
    Bailey Ober logoRB.Ober, P1027.221
    Jorge Alcala logoRJ.Alcala, P201.110
    HITTERSH-ABRHRRBI
    Edouard Julien logo1E.Julien, 2B1-5111
    Byron Buxton logo2B.Buxton, CF2-5102
    Brooks Lee logo2B.Lee, SS0-0000
    Carlos Correa logo3C.Correa, SS2-4100
    Kody Clemens logo3K.Clemens, PH1-1100
    Kody Clemens logo3K.Clemens, 1B1-1100
    Trevor Larnach logo4T.Larnach, RF1-5100
    Ty France logo5T.France, 1B2-4102
    DaShawn Keirsey logo5D.Keirsey, PH0-1000
    DaShawn Keirsey logo5D.Keirsey, LF0-1000
    Ryan Jeffers logo6R.Jeffers, C2-4213
    Mickey Gasper logo7M.Gasper, DH2-5101
    Jonah Bride logo8J.Bride, 3B3-5101
    Harrison Bader logo9H.Bader, LF1-4101
    Harrison Bader logo9H.Bader, CF1-4101
    Guardians Player Stats
    Projected
    PITCHERPCIPKER
    Gavin Williams logoRG.Williams, P61224
    Jakob Junis logoRJ.Junis, P31210
    Paul Sewald logoRP.Sewald, P150.210
    Tim Herrin logoLT.Herrin, P180.102
    Cody Bolton logoRC.Bolton, P40213
    Will Wilson logoRW.Wilson, P26202
    HITTERSH-ABRHRRBI
    Steven Kwan logo1S.Kwan, LF1-3000
    Daniel Schneemann logo1D.Schneemann, 3B1-1000
    Nolan Jones logo2N.Jones, CF0-4000
    Nolan Jones logo2N.Jones, LF0-4000
    Jose Ramirez logo3J.Ramirez, 3B1-3000
    Angel Martinez logo3A.Martinez, CF0-1000
    Kyle Manzardo logo4K.Manzardo, DH1-4000
    Kyle Manzardo logo4K.Manzardo, 1B1-4000
    Carlos Santana logo5C.Santana, 1B2-3000
    Gabriel Arias logo6G.Arias, 2B1-4100
    Bo Naylor logo7B.Naylor, C0-3000
    Austin Hedges logo7A.Hedges, C0-1000
    Jhonkensy Noel logo8J.Noel, RF1-4001
    Brayan Rocchio logo9B.Rocchio, SS0-4000

    Twins vs. Guardians Odds Comparison

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    Twins at Guardians Team Totals

    MatchupOverUnder
    Twins
    34-27
    o3.5-135
    u3.5+105
    Guardians
    33-27
    o4-114
    u4-112