Twins vs. Guardians Odds & Betting Predictions - May 10, 2026
Twins at Guardians
5:40 pm • CLEGStarting Pitchers
| pitcher | team | era | w-l | |
|---|---|---|---|---|
![]() | 3.28 | 5-2 | ||
![]() | 4.96 | 1-1 |
Twins at Guardians Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
|---|---|---|---|---|
Twins 17-23 | N/A | N/A | N/A | |
Guardians 21-20 | N/A | N/A | N/A | |

Progressive FieldCleveland
Twins vs. Guardians Expert Picks
Picks Office
Last 30d: 178-169-11 (-2.8u)
CLE -1-110
1u
Join Discord for earlier access: https://discord.gg/HjKxYKdSUy
Cleveland gets the cleaner starter profile with Gavin Williams at 5-2, 3.28 ERA and 1.09 WHIP.
Minnesota turns to Andrew Morris after Taj Bradley hit the IL, and Morris has 0 starts in the season sample.
The Guardians already beat Minnesota 2-1, 5-4 and 7-4 this season, so -1 fits the matchup without forcing a full -1.5.
Under 7.5-115
1u
Join Discord for earlier access: https://discord.gg/HjKxYKdSUy
Cleveland has scored 3.2 runs per game over its last 10, and this total is still 7.5.
Gavin Williams gives the under a real base at 3.28 ERA, 1.09 WHIP, and 60 strikeouts in 49.1 innings.
The setup helps too. Progressive Field shows 55 degrees, 6 mph wind, and no rain in the matchup window.
YBK Picks.com
Last 30d: 31-21-1 (+16.8u)
CLE -1-110
2u
Sandy Plashkes
Last 30d: 103-100-3 (+12.4u)
MIN +145
1.45u
Cam Is Money
Last 30d: 125-160-4 (-30.6u)
MIN +143
1.43u
Top Shelf Action 🥃
Last 30d: 255-322-16 (+10.1u)
J.Ramirez To Hit 1+ Home Runs Yes+550
0.21u
#EV 18.51%
Over 0.5 (1st Inn)+140
1.27u
#EV 7.13%
Pinny +113
Frank Ammirante
Last 30d: 315-314-9 (+15.6u)
G.Williams o7.5 Ks+120
0.83u
Twins vs. Guardians Previews & Analysis
Prop Odds Comparison
Line Movement Tracker
Twins vs. Guardians Public Betting Percentages
Betting Trends
- Guardians are 3-2 in their last 5 games.
- Guardians are 4-1 in their last 5 games against the spread
- Guardians are 11-12 in their road games against the spread
- The totals have gone OVER in 3 of Guardians' last 5 games
- The totals have gone OVER in 8 of Guardians' 19 last games at home
Matchup History
Against the Spread (ATS) History
Over/Under History
Last 5 Matchups
Guardians vs. Twins Injury Updates

Guardians Injuries

Twins Injuries
- Pablo LopezSP
Lopez is out with elbow
Out
- David FestaSP
Festa is out with shoulder
Out
- Travis AdamsSP
Adams is out with triceps
Out
Twins vs. Guardians Box Score
Twins Player Stats| PITCHER | PC | IP | K | ER | |
|---|---|---|---|---|---|
![]() | 6 | 1 | 0 | 0 | |
![]() | 60 | 3.1 | 5 | 1 | |
![]() | 43 | 1.1 | 2 | 2 | |
![]() | 19 | 1.1 | 2 | 0 | |
![]() | 20 | 1 | 0 | 1 | |
![]() | 10 | 1 | 0 | 0 |
| HITTERS | H-AB | R | HR | RBI |
|---|---|---|---|---|
![]() | 1-4 | 1 | 0 | 0 |
![]() | 1-4 | 0 | 0 | 0 |
![]() | 0-1 | 0 | 0 | 0 |
![]() | 0-0 | 0 | 0 | 0 |
![]() | 1-4 | 0 | 0 | 0 |
![]() | 2-4 | 0 | 0 | 1 |
![]() | 2-3 | 0 | 0 | 1 |
![]() | 0-4 | 0 | 0 | 0 |
![]() | 3-4 | 2 | 0 | 0 |
![]() | 2-3 | 1 | 0 | 1 |
![]() | 1-4 | 1 | 0 | 1 |
Guardians Player Stats| PITCHER | PC | IP | K | ER | |
|---|---|---|---|---|---|
![]() | 101 | 6 | 6 | 5 | |
![]() | 28 | 2 | 1 | 0 | |
![]() | 14 | 1 | 1 | 0 |
| HITTERS | H-AB | R | HR | RBI |
|---|---|---|---|---|
![]() | 0-4 | 0 | 0 | 0 |
![]() | 2-5 | 0 | 0 | 2 |
![]() | 1-4 | 0 | 0 | 1 |
![]() | 0-1 | 1 | 0 | 0 |
![]() | 0-2 | 0 | 0 | 0 |
![]() | 0-2 | 0 | 0 | 0 |
![]() | 1-4 | 0 | 0 | 0 |
![]() | 1-5 | 0 | 0 | 1 |
![]() | 1-3 | 0 | 0 | 0 |
![]() | 0-3 | 0 | 0 | 0 |
![]() | 1-1 | 1 | 0 | 0 |
![]() | 1-1 | 1 | 0 | 0 |
![]() | 4-4 | 2 | 0 | 0 |
Twins vs. Guardians Odds Comparison
Could not load odds
Twins at Guardians Team Totals
MatchupOverUnder | ||
|---|---|---|
Twins 17-23 | N/A | N/A |
Guardians 21-20 | N/A | N/A |
































