White Sox vs. Guardians Odds & Betting Predictions - April 10, 2025

White Sox at Guardians

5:10 pm • CLEG

Chicago White Sox

21-43

1 - 6

Cleveland Guardians

33-29

pitcher		team	era	w-l
G.Williams			3.79	5-3
J.Cannon			4.67	2-7

MatchupOpenSpreadTotalMoneyline
White Sox 21-43	+1.5	+1.5-105	o7.5+100	+205
Guardians 33-29	u7.5	-1.5-114	u7.5-122	-250

Thursday 5:10 p.m.

April 10, 2025

Progressive FieldCleveland

G.Williams o1.5 BB (Live)-155

0.65u

S.Kwan o1.5 Hits + Runs + RBIs-140

0.71u

G.Williams o5.5 Ks-126

0.79u

(CWS) Matt Thaiss o0.5 Batter Walks+145

1.02u

J.Cannon u3.5 Ks+105

Under 0.5 (1st Inn)-125

1.25u

Good to the -135 at Caesars

CLE -1.5-105

0.95u

White Sox bats ice cold – .198 AVG, .534 OPS in 7-game slide. Just 15 runs in that stretch. Injuries piling up – key hitters hurt. Cannon’s command shaky – 3 BB, 2 HBP in last start. Sox bullpen already has 3 blown saves. Guardians pitching locked in – just 1 ER last 2 games. Pen ranks top 3 in WHIP, opp BA. Gavin Williams got hit by CHW in 2024, but this lineup lacks power. Santana hot – batting .364 last 6, 2 HR. CLE lineup due for bounce after low-run wins. Cannon’s 56.5 GB% sets up for damage on gaps. CLE 6-1 vs CHW in last 7, 4-1 at home. Sox 0-5 on road, worst AL run support away. Guardians eyeing sweep behind hot arms, vets clicking.

G.Williams o6.5 Ks+154

0.52u

2.59% ev

MLB NRFI & YRFI Predictions: +550 for Today
Billy Ward•
Apr 10, 2025 UTC
White Sox vs. Guardians: Target Thursday's Total
Tony Sartori•
Apr 10, 2025 UTC

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No props found

MLB Public Betting

Guardians are 2-3 in their last 5 games.
Guardians are 3-2 in their last 5 games against the spread
Guardians are 16-17 in their road games against the spread
The totals have gone OVER in 0 of Guardians' last 5 games
The totals have gone OVER in 12 of Guardians' 29 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Guardians	30-32	14-15	16-17	11-11	19-20
White Sox	37-27	20-12	17-15	N/A	37-27

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Guardians	26-33-3	12-16-1	14-17-2	12-10	14-22-3
White Sox	30-31-3	18-12-2	12-19-1	N/A	30-31-3

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Guardians	33-29	17-12	16-17	15-7	18-21
White Sox	21-43	15-17	6-26	N/A	21-43

date	opponent	score	spread	over/under	moneyline
Apr 9th	CWS	W 3-2	-1.5 L	U 7.5	CLE -168
Apr 8th	CWS	W 1-0	-1.5 L	U 7.5	CLE -202
Apr 6th	@LAA	L 2-6	-1.5 L	U 9.5	LAA -111
Apr 6th	@LAA	L 4-10	-1.5 L	O 9	LAA -152
Apr 5th	@LAA	W 8-6	-1.5 W	O 8	CLE -118

Ben Lively
P
Lively is out with elbow
Out
Shane Bieber
P
Bieber is out with elbow
Out
John Means
P
Means is out with elbow
Out

Ky Bush
P
Bush is out with elbow
Out
Drew Thorpe
P
Thorpe is out with elbow
Out

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PITCHER	PC	IP	K	ER
RJ.Cannon, P	102	5.1	6	6
RB.Wilson, P	19	1.2	0	0
RM.Clevinger, P	6	1	0	0

HITTERS	H-AB	R
1N.Maton, DH	1-3	1
2A.Vaughn, 1B	0-4	0
3M.Vargas, 3B	0-4	0
4M.Thaiss, C	1-3	0
5A.Slater, RF	1-4	0
6L.Sosa, 2B	2-4	0
7B.Baldwin, LF	0-4	0
8M.Taylor, CF	0-2	0
9J.Amaya, SS	0-3	0

PITCHER	PC	IP	K	ER
RG.Williams, P	94	5	7	1
RJ.Junis, P	20	2	1	0
LJ.Cantillo, P	33	2	4	0

HITTERS	H-AB	R	HR	RBI
1S.Kwan, LF	4-5	2	1	4
2J.Ramirez, 3B	0-4	0	0	0
3C.Santana, DH	0-3	0	0	0
4K.Manzardo, 1B	1-4	1	1	2
5N.Jones, CF	1-4	0	0	0
6J.Noel, RF	1-4	1	0	0
7B.Naylor, C	1-3	1	0	0
8D.Schneemann, 2B	0-4	0	0	0
9B.Rocchio, SS	2-3	1	0	0