White Sox vs. Guardians Odds & Betting Predictions - September 12, 2025

White Sox at Guardians

11:10 pm • CLEG

Chicago White Sox

57-91

0 - 4

Cleveland Guardians

76-71

pitcher		team	era	w-l
T.Bibee			4.44	10-11
M.Perez			3.27	1-5

MatchupOpenSpreadTotalMoneyline
White Sox 57-91	+1.5-180	o7.5-110	+119
Guardians 76-71	u8	-1.5+150	u7.5-108	-142

Friday 11:10 p.m.

September 12, 2025

Progressive FieldCleveland

CLE -135

0.5u

I actually don’t consider Martin Perez a gas can but project Cleveland for half a run higher and like how the Cleveland bats profile against him.

Under 7.5-103

1.21u

CLE -139

0.72u

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T.Bibee u5.5 Ks-145

@cowhitchurch https://myaction.app/RW4DhImIBWb

CWS +135

CLE -146

0.5u

Bet to -155

White Sox vs Guardians: Tonight's Over/Under Pick
Action Network Staff•
Sep 12, 2025 UTC

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No props found

MLB Public Betting

Guardians are 4-1 in their last 5 games.
Guardians are 4-1 in their last 5 games against the spread
Guardians are 41-33 in their road games against the spread
The totals have gone OVER in 1 of Guardians' last 5 games
The totals have gone OVER in 34 of Guardians' 73 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Guardians	77-70	36-37	41-33	30-30	46-38
White Sox	87-61	44-31	43-30	0-2	86-59

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Guardians	64-77-6	34-36-3	30-41-3	31-28-1	32-47-5
White Sox	70-71-7	40-30-5	30-41-2	0-2	69-69-7

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Guardians	76-71	39-34	37-37	38-22	38-46
White Sox	57-91	32-43	25-48	1-1	55-90

date	opponent	score	spread	over/under	moneyline
Sep 11th	KC	W 3-2	-	-	CLE -144
Sep 10th	KC	L 3-4	+1.5 W	U 8	KC -110
Sep 9th	KC	W 2-0	+1.5 W	U 7.5	CLE -110
Sep 8th	KC	W 10-2	+1.5 W	O 7.5	CLE -115
Sep 7th	@TB	W 2-1	+1.5 W	U 8	CLE +138

Ben Lively
SP
Lively is out with elbow
Out
John Means
SP
Means is out with elbow
Out

Ky Bush
SP
Bush is out with elbow
Out
Drew Thorpe
SP
Thorpe is out with elbow
Out

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PITCHER		PC	IP	K	ER
LM.Perez, P		96	6.2	3	3
RS.Wilson, P		23	1.1	0	1

HITTERS	H-AB	R	HR	RBI
1M.Tauchman, RF	0-4	0	0	0
2K.Teel, C	0-4	0	0	0
3L.Sosa, 1B	0-4	0	0	0
4C.Montgomery, SS	0-3	0	0	0
5M.Vargas, 3B	0-3	0	0	0
6A.Benintendi, DH	0-3	0	0	0
7B.Baldwin, CF	0-2	0	0	0
7M.Taylor, CF	0-1	0	0	0
8C.Meidroth, 2B	1-3	0	0	0
9W.Robertson, LF	1-2	0	0	0

PITCHER		PC	IP	K	ER
RT.Bibee, P		103	9	10	0

HITTERS	H-AB	R	HR	RBI
1S.Kwan, LF	0-3	0	0	0
2A.Martinez, CF	1-3	1	1	1
3J.Ramirez, 3B	0-4	0	0	0
4D.Fry, DH	1-3	1	1	1
5K.Manzardo, 1B	0-3	0	0	0
6G.Arias, SS	1-3	1	0	0
7J.Noel, RF	1-2	1	0	0
7N.Jones, PH	1-1	0	0	1
7N.Jones, RF	1-1	0	0	1
8B.Rocchio, 2B	0-3	0	0	0
9A.Hedges, C	1-3	0	0	1