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Cleveland Guardians Odds

3rd in division

Next Guardians Game

Game Details
@ New York Yankees
New York
location pin
Wed 6/0411:05 PM

Yankees vs Guardians Odds

More Odds
SpreadTotalMoneyline
CLE
+1.5-125
o9-105
+159
NYY
-1.5+105
u9-115
-191
Cleveland Guardians Team Notes

Guardians Injuries

All MLB Injuries
  • Ben Lively
    SP

    Lively is out with elbow

    Out

  • Shane Bieber
    SP

    Bieber is out with elbow

    Out

  • John Means
    SP

    Means is out with elbow

    Out

Picks
MoneyLineWixted
MoneyLineWixted
Last 30d: 5-10-0 (-3.5u)
1
Picks Office
Picks Office
Last 30d: 71-68-0 (+1.9u)
NYY -1.5+110
CLE
CLE Team Abbreviation@NYY Team Abbreviation
NYY
1u
06/04 11:05 PM
Follow @PicksOffice on X. Yankees 3rd in AVG, 2nd in HRs, 3rd in runs – Bronx Bombers living up to the name. Stadium plays short to RF, perfect for righty-heavy lineup. Ortiz gets punished by power bats. Clarke Schmidt in form – 6 shutout innings vs Angels last start. Yankees bullpen lights-out with 3.42 ERA, 1.12 WHIP – lockdown late. Guardians just 1-4 in Ortiz’s last 5 outings. Offense often stalls – bad combo vs a team that’s 10-3 in their last 13. Yankees pounce early, close late. Cleveland hates the Bronx – 3-7 last 10 vs NYY, 26-58 in last 84 at Yankee Stadium. Yanks 19-9 at home, crowd brings playoff energy. Yankees won series opener, carry momentum. Better team, hotter team, home crowd. Everything points to a decisive W.
5
Billy Ward
Billy Ward
Last 30d: 27-33-4 (-12.1u)
NYY +240 (1st Inn)
CLE
CLE Team Abbreviation@NYY Team Abbreviation
NYY
0.5u
06/04 11:05 PM
Yanks ML at MGM or team YRFI (+180 DK) otherwise
10
Sean Zerillo
Sean Zerillo
Last 30d: 122-116-7 (+0.7u)
Over 9+100
CLE
CLE Team Abbreviation@NYY Team Abbreviation
NYY
0.5u
06/04 11:05 PM
Bet to -105
124
Boomer Betz
Boomer Betz
Last 30d: 66-104-0 (-28.3u)
Sean Zerillo
Sean Zerillo
Last 30d: 122-116-7 (+0.7u)
NYY -182
CLE
CLE Team Abbreviation@NYY Team Abbreviation
NYY
0.5u
06/04 11:05 PM
Flat to -190
139

Guardians 2025 Schedule & Betting Odds

dateopponentscorespreadover/undermoneyline
Jun 6thHOU----
Jun 5th@NYY----
Jun 4th@NYY----
Jun 3rd@NYYL 2-3+1.5 WU 8NYY +166
Jun 1stLAAW 4-2-1.5 WU 8CLE -210
May 31stLAAW 7-5-1.5 WO 8CLE -169
May 30thLAAL 1-4-1.5 LU 8.5LAA -142
May 28thLADW 7-4+1.5 WO 9CLE +145
May 27thLADL 5-9+1.5 LO 9LAD +114
May 26thLADL 2-7+1.5 LO 7.5LAD +152
News
  • Guardians vs. Yankees: +250 SGP for Wednesday article feature image

    Guardians vs. Yankees: +250 SGP for Wednesday

    Dead President Picks
    Jun 4, 2025 UTC
  • MLB NRFI & YRFI: 3 Picks for Wednesday article feature image

    MLB NRFI & YRFI: 3 Picks for Wednesday

    Billy Ward
    Jun 4, 2025 UTC
  • Zerillo's Tuesday MLB Predictions & Betting Card article feature image

    Zerillo's Tuesday MLB Predictions & Betting Card

    Sean Zerillo
    Jun 3, 2025 UTC
  • Guardians vs. Yankees MLB Betting Promos: Earn Up to $3,600 in Sign-Up Bonuses for TBS Game Tonight article feature image

    Guardians vs. Yankees MLB Betting Promos: Earn Up to $3,600 in Sign-Up Bonuses for TBS Game Tonight

    Daniel Preciado
    Jun 3, 2025 UTC

Cleveland Guardians 2025 Season Preview

The Cleveland Guardians enter the 2025 MLB season with a blend of anticipation and determination following an exciting season, where they captured the AL Central title and beat division rival, Detroit, in the ALDS. However, after this great season, the Guardians followed it up with a relatively quiet offseason.

Key players like Jose Ramirez and Shane Bieber remain central to the team's success, with Ramirez providing offensive firepower and Bieber anchoring the pitching rotation. The Guardians' defensive prowess is expected to shine, with projections placing them as the best defensive team in the league, signaling a strong foundation for success. Bieber was on an absolute tear to start last year, but suffered from Tommy John - Cleveland re-signed him this offseason as he is expected to make a full recovery.

The Guardians will look a little new in their lineup as Josh Naylor and Andres Gimenez were both traded this past offseason in an effort to revamp the lineup. Guardian fans will see a familiar face in the lineup with Carlos Santana coming back to the fold on a one-year deal. Heading into the 2025 season, the Guardians will continue to rely on their steady pitching, elite fielding, and top-tier baserunning.

Betting on the Cleveland Guardians

Here are some examples of placing bets on Cleveland Guardians.

Guardians Spread (Run Line)

When betting on baseball, you’ll be faced with three standard options: the moneyline, over/under and run line.

The run line is a bet on the margin of victory, like a point spread. But because baseball is low scoring, the spread will almost always be -1.5 for the favorite and +1.5 for the underdog. The payouts for each will just be adjusted based on each team’s strength.

Here’s a brief example of a run line for a hypothetical Guardians game:

  • St. Louis Cardinals (+1.5)
  • Cleveland Guardians (-1.5)

As shown above, the Guardians are favored by 1.5 runs against the Cardinals; the minus sign (-) indicates Cleveland is the favorite, while a plus sign (+) is used to denote the underdog. Bettors who wanted to back Cleveland here would be “laying” those 1.5 runs, meaning for their bets to cash the Guardians would need to win by two runs or more. Bettors who selected the Cardinals +1.5 would win if St. Louis won outright or kept a loss to 1 run.

Guardians Moneylines

Many first time bettors are wary of run line bets, especially when riding with the hometown team. In that case, moneyline wagers are often seen as the safer way to go. A moneyline bet is a bet on who wins the game -- no run line involved.

Let’s use the same example from before to understand the moneyline better:

  • St. Louis Cardinals +150
  • Cleveland Guardians -180

Just as with run lines, the minus sign (-) signifies a team is favored, while the plus sign (+) means a team is the underdog. The moneyline odds, written in American odds format here, indicate how big or small a favorite that team is, written in increments of $100. For example, to win $100 on the Guardians, a bettor would need to risk $180. On the flip side, a $100 bet on the Cardinals would net $150 if they pulled the upset.

Odds can differ from sportsbook to sportsbook, so always make sure you shop for the best line with The Action Network app.

Guardians Over/Unders

Betting on a team to win or cover a run line isn’t the only type of wager allowed on MLB games. Almost all sportsbooks will offer a total on the game, also known as an over/under. This bet is not on the winner of the contest, but on the number of runs the two teams will combine to score; sportsbooks hang a number, and bettors can wager either over or under that total.

If the number for our hypothetical Guardians-Cardinals matchup was 8 runs, over bettors would require 9 points or more to cash their tickets, while those who bet the under would need 7 or fewer runs. If the two teams scored exactly 8 runs between them, that bet would push and all wagers would be refunded.

Guardians Props

Some bettors find more entertainment and success betting on more specific outcomes than the result of the game. Prop bets cover a wide market of wagers on player stats, discrete in-game events, and any style of yes/no question. Many props are bets on specific players and their performance, such as betting Jose Ramirez over 1.5 hits on a given night, or betting that Shane Bieber will strike out over 9.5 batters. Some props can be shorter term, such as betting on the number of runs scored in the first five innings or who will hit a home run. Offerings tend to vary depending on the sportsbook, so use our sportsbook reviews to find the best bet for you.

Guardians Futures

Expectations are rising right now in Cleveland, so bettors will have to shop for the best line to get good odds on Guardians futures bets. Futures are bets that focus on long term outcomes, like the Guardians to win the AL Central, win the American League Pennant, win the World Series, or even individual awards like winning league MVP.

How to Bet on the Cleveland Guardians

Online sports betting is now legal in Ohio. Legalized Ohio sports betting has launched on Jan. 1, 2023. Now that the sports betting is live in The Buckeye State, you are able to place wagers on the Reds through the nation's top sportsbooks.Here are a few great options to choose from: BetMGM , FanDuel , Caesars , bet365  and PointsBet .

BetMGM Sportsbook

BetMGM offers new and veteran bettors alike a terrific betting experience with a simple and sleek desktop and mobile design. Read our BetMGM Sportsbook review for more information about our BetMGM bonus code and instructions on how to sign up.

Caesars Sportsbook

Another great option for new sports bettors is Caesars Sportsbook. Read our Caesars review for more information about our Ceasars Sportsbook promo code and instructions on how to sign up.

PrizePicks

If you're looking for a different type of action, PrizePicks is a great option for daily fantasy sports. PrizePicks is among the most simple and exciting DFS games in North America because users just have to place their bets, pick their favorite players, and choose over/under totals for a chance to win cash. New users can claim a deposit match on up to $100. Sign up using our PrizePicks Promo Code now!

Frequently Asked Questions
How many World Series titles have the Cleveland Guardians won?
Right Arrow

Next Guardians Game

Game Details
@ New York Yankees
New York
location pin
Wed 6/0411:05 PM

Yankees vs Guardians Odds

More Odds
SpreadTotalMoneyline
CLE
+1.5-125
o9-105
+159
NYY
-1.5+105
u9-115
-191

Guardians Injuries

All MLB Injuries
  • Ben Lively
    SP

    Lively is out with elbow

    Out

  • Shane Bieber
    SP

    Bieber is out with elbow

    Out

  • John Means
    SP

    Means is out with elbow

    Out

Cleveland Guardians 2025 Season Preview

The Cleveland Guardians enter the 2025 MLB season with a blend of anticipation and determination following an exciting season, where they captured the AL Central title and beat division rival, Detroit, in the ALDS. However, after this great season, the Guardians followed it up with a relatively quiet offseason.

Key players like Jose Ramirez and Shane Bieber remain central to the team's success, with Ramirez providing offensive firepower and Bieber anchoring the pitching rotation. The Guardians' defensive prowess is expected to shine, with projections placing them as the best defensive team in the league, signaling a strong foundation for success. Bieber was on an absolute tear to start last year, but suffered from Tommy John - Cleveland re-signed him this offseason as he is expected to make a full recovery.

The Guardians will look a little new in their lineup as Josh Naylor and Andres Gimenez were both traded this past offseason in an effort to revamp the lineup. Guardian fans will see a familiar face in the lineup with Carlos Santana coming back to the fold on a one-year deal. Heading into the 2025 season, the Guardians will continue to rely on their steady pitching, elite fielding, and top-tier baserunning.

Betting on the Cleveland Guardians

Here are some examples of placing bets on Cleveland Guardians.

Guardians Spread (Run Line)

When betting on baseball, you’ll be faced with three standard options: the moneyline, over/under and run line.

The run line is a bet on the margin of victory, like a point spread. But because baseball is low scoring, the spread will almost always be -1.5 for the favorite and +1.5 for the underdog. The payouts for each will just be adjusted based on each team’s strength.

Here’s a brief example of a run line for a hypothetical Guardians game:

  • St. Louis Cardinals (+1.5)
  • Cleveland Guardians (-1.5)

As shown above, the Guardians are favored by 1.5 runs against the Cardinals; the minus sign (-) indicates Cleveland is the favorite, while a plus sign (+) is used to denote the underdog. Bettors who wanted to back Cleveland here would be “laying” those 1.5 runs, meaning for their bets to cash the Guardians would need to win by two runs or more. Bettors who selected the Cardinals +1.5 would win if St. Louis won outright or kept a loss to 1 run.

Guardians Moneylines

Many first time bettors are wary of run line bets, especially when riding with the hometown team. In that case, moneyline wagers are often seen as the safer way to go. A moneyline bet is a bet on who wins the game -- no run line involved.

Let’s use the same example from before to understand the moneyline better:

  • St. Louis Cardinals +150
  • Cleveland Guardians -180

Just as with run lines, the minus sign (-) signifies a team is favored, while the plus sign (+) means a team is the underdog. The moneyline odds, written in American odds format here, indicate how big or small a favorite that team is, written in increments of $100. For example, to win $100 on the Guardians, a bettor would need to risk $180. On the flip side, a $100 bet on the Cardinals would net $150 if they pulled the upset.

Odds can differ from sportsbook to sportsbook, so always make sure you shop for the best line with The Action Network app.

Guardians Over/Unders

Betting on a team to win or cover a run line isn’t the only type of wager allowed on MLB games. Almost all sportsbooks will offer a total on the game, also known as an over/under. This bet is not on the winner of the contest, but on the number of runs the two teams will combine to score; sportsbooks hang a number, and bettors can wager either over or under that total.

If the number for our hypothetical Guardians-Cardinals matchup was 8 runs, over bettors would require 9 points or more to cash their tickets, while those who bet the under would need 7 or fewer runs. If the two teams scored exactly 8 runs between them, that bet would push and all wagers would be refunded.

Guardians Props

Some bettors find more entertainment and success betting on more specific outcomes than the result of the game. Prop bets cover a wide market of wagers on player stats, discrete in-game events, and any style of yes/no question. Many props are bets on specific players and their performance, such as betting Jose Ramirez over 1.5 hits on a given night, or betting that Shane Bieber will strike out over 9.5 batters. Some props can be shorter term, such as betting on the number of runs scored in the first five innings or who will hit a home run. Offerings tend to vary depending on the sportsbook, so use our sportsbook reviews to find the best bet for you.

Guardians Futures

Expectations are rising right now in Cleveland, so bettors will have to shop for the best line to get good odds on Guardians futures bets. Futures are bets that focus on long term outcomes, like the Guardians to win the AL Central, win the American League Pennant, win the World Series, or even individual awards like winning league MVP.

How to Bet on the Cleveland Guardians

Online sports betting is now legal in Ohio. Legalized Ohio sports betting has launched on Jan. 1, 2023. Now that the sports betting is live in The Buckeye State, you are able to place wagers on the Reds through the nation's top sportsbooks.Here are a few great options to choose from: BetMGM , FanDuel , Caesars , bet365  and PointsBet .

BetMGM Sportsbook

BetMGM offers new and veteran bettors alike a terrific betting experience with a simple and sleek desktop and mobile design. Read our BetMGM Sportsbook review for more information about our BetMGM bonus code and instructions on how to sign up.

Caesars Sportsbook

Another great option for new sports bettors is Caesars Sportsbook. Read our Caesars review for more information about our Ceasars Sportsbook promo code and instructions on how to sign up.

PrizePicks

If you're looking for a different type of action, PrizePicks is a great option for daily fantasy sports. PrizePicks is among the most simple and exciting DFS games in North America because users just have to place their bets, pick their favorite players, and choose over/under totals for a chance to win cash. New users can claim a deposit match on up to $100. Sign up using our PrizePicks Promo Code now!

Frequently Asked Questions
How many World Series titles have the Cleveland Guardians won?
Right Arrow