Kansas vs. Iowa State Odds & Betting Predictions - November 22, 2025

Kansas at Iowa State

5:00 pm • Fox Sports 1

Kansas Jayhawks

14

14 - 38

Iowa State Cyclones

38

MatchupOpenSpreadTotalMoneyline
Kansas 0-0	+3.5	+3.5-116	o55.5-109	+137
Iowa State 0-0	u53.5	-3.5-108	u55.5-110	-163

location pin

Saturday 5:00 p.m.

November 22, 2025

Jack Trice StadiumAmes

KU +13.5 (Live)-110

1.1u

ISU -3.5-105

1.04u

Over 55.5+105

0.7u

2.75% ev

KU +145 (1H)

0.8u

4.41% ev

ISU -2.5 (1H)-125

0.5u

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No props found

NCAAF Public Betting

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Iowa State	N/A	N/A	N/A	N/A	N/A
Kansas	N/A	N/A	N/A	N/A	N/A

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Iowa State	N/A	N/A	N/A	N/A	N/A
Kansas	N/A	N/A	N/A	N/A	N/A

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Iowa State	N/A	N/A	N/A	N/A	N/A
Kansas	N/A	N/A	N/A	N/A	N/A

date	opponent	score	spread	over/under	moneyline
Nov 8th	@TCU	W 20-17	+7.5 W	U 58	ISU +242
Nov 1st	ASU	L 19-24	-7.5 L	U 48.5	ASU -330
Oct 25th	BYU	L 27-41	-2.5 L	O 49	BYU -146
Oct 11th	@COLO	L 17-24	-3 L	U 52	COLO -154
Oct 4th	@CIN	L 30-38	+1.5 L	O 55.5	CIN +100

Total

323

Total Yards

462

50

Total Plays

73

6.46

Yards Per Play

6.328767123287672

Passing

191

YDS

241

16/29

Comps/Atts

18/23

6.586206896551724

YPA

10.478260869565217

1/1

TDs/INTs

3/0

0/0

Sacks/Yards

1/2

Rushing

132

Rush Yards

221

21

Attempts

50

6.285714285714286

YPC

4.42

1

TDs

2

Turnovers

0

Fumbles Lost

0

1

Interceptions

0

Efficiency

1/3 33.33%

Redzone

4/4 100%

5/9 0%

3rd Down

9/16 0%

0/1 0%

4th Down

4/5 0%

First Downs

17

Total

25

10

Pass

13

6

Rush

11

1

Penalty

1

Misc

4/25

Penalties/Yards

3/30

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MatchupOverUnder
Kansas 0-0	N/A	N/A
Iowa State 0-0	N/A	N/A