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Cyclones vs. Buffaloes Odds & Betting Predictions - October 11, 2025

Cyclones at Buffaloes

7:30 pm • ESPN

Iowa State Cyclones

8-4
17
17 - 24

Colorado Buffaloes

3-9
24

Cyclones at Buffaloes Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Cyclones
8-4
-4.5
-3-110
o52-110
-154
Buffaloes
3-9
u52.5
+3-110
u52-110
+128
location pinSaturday 7:30 p.m.
October 11, 2025
Folsom FieldBoulder
Cyclones vs. Buffaloes Expert Picks
Jeremiah Rose
Jeremiah Rose
Last 30d: 34-30-1 (-0.5u)
ISU -2-130
0.25u
Boyd / FanDuel
K.Salter Anytime TD Scorer Yes+120
0.2u
YBK Picks.com
Last 30d: 42-38-0 (-0.3u)
COLO +3-105
1.9u
Sandy Plashkes
Sandy Plashkes
Last 30d: 107-128-0 (-44.6u)
COLO +3-110
1u
Brian Bitler
Brian Bitler
Last 30d: 91-79-0 (+15.4u)
COLO +2.5+102
3.06u
Dan Gaspar
Dan Gaspar
Last 30d: 30-28-5 (-1.8u)
K.Salter Anytime TD Scorer Yes+120
1u
K.Salter o33.5 Rush Yds-114
1u
Big Bets On Campus (CFB)
Big Bets On Campus (CFB)
Last 30d: 68-69-2 (-2.2u)
COLO +114
1u
@_Collin1 ML Underdog https://myaction.app/1vE4iyi3lXb
Collin Wilson
Collin Wilson
Last 30d: 53-35-2 (+13.5u)
COLO +3-120
1u
Duck
Duck
Last 30d: 97-96-1 (-7.3u)
Over 51.5-115
1.15u
Gobble up those last 51.5’s Iowa state grades out as the worst rated pass rush and worst tackling team per PFF in B12 play. Colorado the worst coverage unit in the conference per PFF and Iowa state should be down there too based on injuries and who is playing at corner. Buffs 125th in defensive success rate, 91 in explosives given up. Iowa state 119th in pass play explosives given up.

Cyclones vs. Buffaloes Previews & Analysis

  • The Big Bets On Campus Weekend Warmup! | College Football Week 7 article feature image

    The Big Bets On Campus Weekend Warmup! | College Football Week 7

    Mike Calabrese•
    Oct 17, 2025 UTC
  • Iowa State vs Colorado: Injuries to Impact Over/Under article feature image

    Iowa State vs Colorado: Injuries to Impact Over/Under

    Doug Ziefel•
    Oct 11, 2025 UTC
  • Our College Football Best Bets For Saturday's Afternoon Slate article feature image

    Our College Football Best Bets For Saturday's Afternoon Slate

    Action Network Staff•
    Oct 11, 2025 UTC
  • Stuckey & Wilson: Our Top ML Dogs for Week 7 article feature image

    Stuckey & Wilson: Our Top ML Dogs for Week 7

    Collin Wilson•
    Oct 11, 2025 UTC
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Prop Odds Comparison

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Line Movement Tracker

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Cyclones vs. Buffaloes Public Betting Percentages

Away Logo

Cyclones

Public

Home Logo

Buffaloes

57%

Bets%

43%

Money%

NCAAF Public Betting Right Arrow

Betting Trends

  • Buffaloes are 1-4 in their last 5 games.
  • Buffaloes are 1-4 in their last 5 games against the spread
  • Buffaloes are 1-4 in their road games against the spread
  • The totals have gone OVER in 3 of Buffaloes' last 5 games
  • The totals have gone OVER in 3 of Buffaloes' 7 last games at home

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Buffaloes		5-74-31-42-03-7
Cyclones		5-73-31-43-62-1

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Buffaloes		5-73-42-31-14-6
Cyclones		4-83-31-43-61-2

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Buffaloes		3-9N/AN/A2-01-9
Cyclones		8-4N/AN/A6-32-1

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Oct 4th@TCUL 21-35+13.5 LU 57.5TCU +400
Sep 28thBYUL 21-24+6.5 WU 48.5BYU +205
Sep 21stWYOW 37-20-12.5 WO 45.5COLO -470
Sep 12th@HOUL 20-36+4 LO 45.5HOU +160
Sep 6thDELW 31-7-23.5 WU 49.5COLO -2800
Team Stats

Total

441
Total Yards
395
70
Total Plays
64
6.3
Yards Per Play
6.171875

Passing

205
YDS
255
18/33
Comps/Atts
16/25
6.212121212121212
YPA
10.2
0/1
TDs/INTs
2/0
0/0
Sacks/Yards
0/0

Rushing

236
Rush Yards
140
37
Attempts
39
6.378378378378378
YPC
3.58974358974359
2
TDs
1

Turnovers

0
Fumbles Lost
0
1
Interceptions
0

Efficiency

3/4 75%
Redzone
3/3 100%
2/12 0%
3rd Down
7/15 0%
0/1 0%
4th Down
0/1 0%

First Downs

22
Total
16
12
Pass
9
9
Rush
6
1
Penalty
1

Misc

7/59
Penalties/Yards
6/43

Cyclones vs. Buffaloes Odds Comparison

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Cyclones at Buffaloes Team Totals

MatchupOverUnder
Cyclones
8-4
o27.5-114
u27.5-114
Buffaloes
3-9
o24.5-104
u24.5-126