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Michigan St vs. Iowa Odds & Betting Predictions - November 22, 2025

Michigan St at Iowa

8:30 pm • Fox Sports 1

Michigan State Spartans

4-8
17
17 - 20

Iowa Hawkeyes

8-4
20

Michigan St at Iowa Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Michigan St
4-8
+17.5
+17.5-115
o42.5-111
+587
Iowa
8-4
u43.5
-17.5-106
u42.5-110
-900
location pinSaturday 8:30 p.m.
November 22, 2025
Kinnick StadiumIowa City
Michigan St vs. Iowa Expert Picks
Jeremiah Rose
Jeremiah Rose
Last 30d: 38-32-1 (+0.6u)
IOWA -16-120
0.5u
Boomer’s Book
Sean Zerillo
Sean Zerillo
Last 30d: 72-63-1 (+5.9u)
MSU +17.5-115
0.25u
Greg Matherne
Greg Matherne
Last 30d: 26-14-0 (+5.4u)
MSU +17-109
0.5u
Dan Gaspar
Dan Gaspar
Last 30d: 40-31-2 (+5.1u)
K.Moulton o6.5 Rec Yds-115
1u
N.Marsh o35.5 Rec Yds-115
1.15u
Babs .
Babs .
Last 30d: 118-80-0 (+25.8u)
MSU +17-113
0.88u

Michigan St vs. Iowa Previews & Analysis

  • Michigan State vs. Iowa: Hawkeyes Will Roll article feature image

    Michigan State vs. Iowa: Hawkeyes Will Roll

    Action Analytics•
    Nov 22, 2025 UTC
  • Your Week 13 NCAAF Betting Cheat Sheet article feature image

    Your Week 13 NCAAF Betting Cheat Sheet

    Pete Ruden•
    Nov 22, 2025 UTC
  • Picks For USC vs. Oregon & More College Football Week 13 Bets & Parlays! | Big Bets On Campus article feature image

    Picks For USC vs. Oregon & More College Football Week 13 Bets & Parlays! | Big Bets On Campus

    •
    Nov 21, 2025 UTC
  • The Big Bets On Campus Weekend Warmup! | College Football Week 13 article feature image

    The Big Bets On Campus Weekend Warmup! | College Football Week 13

    Joshua Nunn•
    Nov 21, 2025 UTC
See more NCAAF Coverage Right Arrow

Prop Odds Comparison

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No props found

Line Movement Tracker

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Michigan St vs. Iowa Public Betting Percentages

Away Logo

Michigan St

Public

Home Logo

Iowa

48%

Bets%

52%

Money%

NCAAF Public Betting Right Arrow

Betting Trends

  • Iowa are 4-1 in their last 5 games.
  • Iowa are 3-2 in their last 5 games against the spread
  • Iowa are 5-0 in their road games against the spread
  • The totals have gone OVER in 3 of Iowa' last 5 games
  • The totals have gone OVER in 3 of Iowa' 7 last games at home

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Iowa		9-34-35-04-34-0
Michigan St		7-51-55-01-46-1

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Iowa		5-73-42-34-30-4
Michigan St		7-53-33-23-24-3

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Iowa		8-4N/AN/A7-00-4
Michigan St		4-8N/AN/A4-10-7

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Nov 15th@USCL 21-26+6.5 WU 48.5USC +192
Nov 8thOREL 16-18+4.5 WU 41.5ORE +170
Oct 25thMINNW 41-3-7.5 WO 39.5IOWA -300
Oct 18thPSUW 25-24-3.5 LO 41.5IOWA -162
Oct 11th@WISW 37-0-5.5 WU 37.5IOWA -230
Team Stats

Total

335
Total Yards
301
69
Total Plays
61
4.855072463768116
Yards Per Play
4.934426229508197

Passing

255
YDS
147
25/42
Comps/Atts
12/22
6.071428571428571
YPA
6.681818181818182
2/1
TDs/INTs
1/1
2/17
Sacks/Yards
3/8

Rushing

80
Rush Yards
154
27
Attempts
39
2.962962962962963
YPC
3.948717948717949
0
TDs
0

Turnovers

0
Fumbles Lost
1
1
Interceptions
1

Efficiency

2/2 100%
Redzone
2/2 100%
4/15 0%
3rd Down
1/10 0%
0/1 0%
4th Down
0/1 0%

First Downs

18
Total
16
11
Pass
7
5
Rush
9
2
Penalty
0

Misc

1/10
Penalties/Yards
4/40

Michigan St vs. Iowa Odds Comparison

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Michigan St at Iowa Team Totals

MatchupOverUnder
Michigan St
4-8
o12.5-130
u12.5-112
Iowa
8-4
o29.5-122
u29.5-110