Cardinals vs. Marlins Odds & Betting Predictions - April 21, 2026

Cardinals at Marlins

10:40 pm • MIAM

St. Louis Cardinals

14-9

5 - 3

Miami Marlins

11-13

pitcher		team	era	w-l
C.Paddack			6.38	0-4
D.May			5.84	3-2

MatchupOpenSpreadTotalMoneyline
Cardinals 14-9	+1.5	-1.5+153	o8.5-120	+101
Marlins 11-13	u8.5	+1.5-186	u8.5-101	-123

Tuesday 10:40 p.m.

April 21, 2026

loanDepot parkMiami

Over 8.5-105

1.05u

Under 8.5+100

0.5u

STL +100

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X.Edwards o0.5 SB+575

0.2u

Targetting Dustin May with a couple LHB with speed. He’s allowed a 1.58 WHIP in 2025 & 1.95 in 2026 vs LHB. He allowed 15 SBs on 21 Att since last season & continues to allow big leads & jumps to baserunners. I’m expecting Miami to be aggressive on the bases tonight.

J.Marsee o0.5 SB+475

0.25u

D.May o16.5 Outs-106

1.06u

D.May u2.5 Earned Runs-125

STL -102

STL -110 (F5)

Under 8.5-103

0.5u

Bet to -110

J.Walker o0.5 HR+460

@gneiffer07 ⭐️⭐️⭐️ https://myaction.app/IPqH1gLpw2b

STL +100

0.5u

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No props found

MLB Public Betting

Marlins are 2-3 in their last 5 games.
Marlins are 2-3 in their last 5 games against the spread
Marlins are 3-6 in their road games against the spread
The totals have gone OVER in 2 of Marlins' last 5 games
The totals have gone OVER in 8 of Marlins' 15 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Marlins	9-15	6-9	3-6	6-9	3-6
Cardinals	14-9	7-5	7-4	1-1	13-8

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Marlins	14-8-2	8-7	6-1-2	8-7	6-1-2
Cardinals	13-9-1	7-5	6-4-1	1-1	12-8-1

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Marlins	11-13	9-6	2-7	9-6	2-7
Cardinals	14-9	7-5	7-4	1-1	13-8

date	opponent	score	spread	over/under	moneyline
Apr 20th	STL	W 5-3	-1.5 W	U 8.5	MIA -138
Apr 19th	MIL	W 5-3	+1.5 W	O 7.5	MIA -115
Apr 18th	MIL	L 2-5	+1.5 L	U 7.5	MIL -119
Apr 17th	MIL	L 5-7	-	O 8	MIL -115
Apr 15th	@ATL	L 3-6	+1.5 L	U 9	ATL +135

Lars Nootbaar
LF
Nootbaar is out with heel
Out
Hunter Dobbins
SP
Dobbins is out with knee
Out

Esteury Ruiz
LF
Ruiz is out with oblique
Out
Maximo Acosta
SS
Acosta is out with oblique
Out
Christopher Morel
LF
Christopher Morel (left oblique) scratched Friday.
Out
Adam Mazur
SP
Mazur is out with elbow
Out

See more MLB Injuries

PITCHER	PC	IP	K	ER
RD.May, P	97	5.1	5	1
LJ.Bruihl, P	27	1.2	0	0
RR.Stanek, P	32	0.2	2	2
RG.Soriano, P	6	0.1	1	0
RR.O'Brien, P	17	1	1	0

HITTERS	H-AB	R	HR	RBI
1J.Wetherholt, 2B	1-4	2	0	0
2I.Herrera, DH	2-5	0	0	0
3A.Burleson, 1B	2-4	1	0	2
4J.Walker, RF	0-4	0	0	0
5N.Gorman, 3B	1-4	0	0	1
6M.Winn, SS	2-4	1	0	0
7N.Church, LF	2-4	1	1	2
8P.Pages, C	0-4	0	0	0
9V.Scott, CF	0-3	0	0	0

PITCHER	PC	IP	K	ER
RC.Paddack, P	90	4.2	7	5
LJ.King, P	19	1.1	2	0
RT.Phillips, P	40	3	3	0

HITTERS	H-AB	R	HR	RBI
1J.Marsee, CF	3-4	1	1	1
2K.Stowers, LF	0-4	0	0	0
2K.Stowers, RF	0-4	0	0	0
3O.Lopez, SS	0-5	0	0	0
4X.Edwards, 2B	2-4	1	0	0
5L.Hicks, C	0-3	1	0	0
6A.Ramirez, DH	0-4	0	0	0
7O.Caissie, RF	0-2	0	0	0
7A.Slater, PH	0-1	0	0	0
7J.Sanoja, 3B	0-0	0	0	0
8G.Pauley, 3B	1-2	0	0	0
8H.Hernandez, PH	1-1	0	0	2
8H.Hernandez, LF	1-1	0	0	2
9C.Norby, 1B	1-4	0	0	0