Guardians vs. Athletics Odds & Betting Predictions - June 22, 2025

Guardians at Athletics

2:05 am • NBCS-CA
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@
Starting Pitchers
pitcherteameraw-l
Mitch Spence logoM.SpenceAthletics logo3.502-1
Luis L. Ortiz logoL.OrtizCleveland Guardians logo4.643-8

Guardians at Athletics Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Guardians
37-37
-1.5
-1.5+119
o9.5+100
-135
Athletics
32-46
u9.5
+1.5-145
u9.5-122
+114
location pinSunday 2:05 a.m.
June 22, 2025
Sutter Health ParkWest Sacramento
Guardians vs. Athletics Expert Picks
Cam Is Money
Cam Is Money
Last 30d: 111-135-0 (-13.7u)
Over 9.5-103
2u
Kyle Murray
Kyle Murray
Last 30d: 67-87-2 (+14.7u)
M.Spence o4.5 Ks+106
1u
Grant Neiffer
Grant Neiffer
Last 30d: 18-109-6 (-17.3u)
N.Kurtz o0.5 HR+450
0.25u
Picks Office
Picks Office
Last 30d: 87-75-2 (+12.2u)
CLE -120
1u
Follow @PicksOffice on X to read the full writeup.
Boomer Betz
Boomer Betz
Last 30d: 197-203-3 (+8.3u)
M.Spence o2.5 Earned Runs+117
1u
Sean Zerillo
Sean Zerillo
Last 30d: 146-143-3 (+6.0u)
ATH +104
0.5u
Bet to -110

Guardians vs. Athletics Previews & Analysis

  • Guardians vs. Athletics: The PRO Model Play article feature image

    Guardians vs. Athletics: The PRO Model Play

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    Jun 21, 2025 UTC
  • Neiffer's Home Run Prop Bets for Saturday article feature image

    Neiffer's Home Run Prop Bets for Saturday

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    Jun 21, 2025 UTC
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Prop Odds Comparison

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Line Movement Tracker

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Guardians vs. Athletics Public Betting Percentages

Away Logo

Guardians

Public

54%

Bets%

46%

Money%

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Athletics
38-4017-2321-176-1132-28
Guardians
37-3717-1720-2013-1324-23

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Athletics
42-31-524-15-118-16-48-7-234-23-3
Guardians
30-40-415-18-115-22-313-1317-26-4

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Athletics
32-4615-2517-218-923-37
Guardians
37-3719-1518-2216-1021-26

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Jun 21stCLEW 5-1+1.5 WU 9ATH +105
Jun 20thHOUW 6-4+1.5 WU 10ATH +122
Jun 19thHOUL 4-11+1.5 LO 9.5HOU +152
Jun 18thHOUL 3-13+1.5 LO 11HOU +107
Jun 17thHOUW 3-1+1.5 WU 9.5ATH -106

Guardians vs. Athletics Injury Updates

Guardians Injuries

  • Ben Lively
    SP

    Lively is out with elbow

    Out

  • Shane Bieber
    SP

    Bieber is out with elbow

    Out

  • John Means
    SP

    Means is out with elbow

    Out

Athletics Injuries

  • Luis Medina
    SP

    Medina is out with elbow

    Out

  • J.T. Ginn
    SP

    Ginn is out with elbow

    Out

  • Ken Waldichuk
    SP

    Waldichuk is out with elbow

    Out

  • Zack Gelof
    2B

    Gelof is out with hand

    Out

  • Brett Harris
    3B

    Harris is out with oblique

    Out

  • Brady Basso
    RP

    Basso is out with shoulder

    Out

Guardians vs. Athletics Starting Lineups
Guardians Starting Lineup
Projected
PITCHERW-LERAWHIPK/9
Luis L. Ortiz logoRL.Ortiz, P3-84.641.4679.63
HITTERSAVGOBPSLGHR
Steven Kwan logo1S.Kwan, LF.299.362.4206
Kyle Manzardo logo2K.Manzardo, DH.212.295.43411
Jose Ramirez logo3J.Ramirez, 3B.317.378.52813
Carlos Santana logo4C.Santana, 1B.241.335.3638
Daniel Schneemann logo5D.Schneemann, SS.241.320.4328
Nolan Jones logo6N.Jones, CF.218.302.3243
Bo Naylor logo7B.Naylor, C.175.285.3749
Johnathan Rodriguez logo8J.Rodriguez, RF.160.192.2800
Angel Martinez logo9A.Martinez, 2B.246.265.3795
Athletics Starting Lineup
Projected
PITCHERW-LERAWHIPK/9
Mitch Spence logoRM.Spence, P2-13.501.2417.83
HITTERSAVGOBPSLGHR
Lawrence Butler logo1L.Butler, RF.264.325.45911
Jacob Wilson logo2J.Wilson, SS.358.397.5059
Brent Rooker logo3B.Rooker, LF.271.348.47715
Nick Kurtz logo4N.Kurtz, DH.252.307.52610
Max Muncy logo5M.Muncy, 3B.202.244.3555
Tyler Soderstrom logo6T.Soderstrom, 1B.249.334.44214
JJ Bleday logo7J.Bleday, CF.197.291.3738
Luis Urias logo8L.Urias, 2B.253.342.4007
Austin Wynns logo9A.Wynns, C.167.200.4582

Guardians vs. Athletics Odds Comparison

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Guardians at Athletics Team Totals

MatchupOverUnder
Guardians
37-37
N/A
N/A
Athletics
32-46
N/A
N/A