Padres vs. Cubs Odds & Betting Predictions - April 4, 2025
Padres at Cubs
6:20 pm • SDPAStarting Pitchers
| pitcher | team | era | w-l | |
|---|---|---|---|---|
![]() | 3.73 | 9-8 | ||
![]() | 3.84 | 6-7 |
Padres at Cubs Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
|---|---|---|---|---|
Padres 1-2 | +1.5 | +1.5-163 | o7-108 | +144 |
Cubs 4-4 | u6.5 | -1.5+137 | u7-112 | -171 |

Wrigley FieldChicago
Padres vs. Cubs Expert Picks
Gamblers Dream
Last 30d: 1-3-0 (-3.5u)
SD +1.5 (Live)+175
1u
The Degenerate
Last 30d: 0-0-0 (+0.0u)
R.Vasquez u155 Outs (Live)-115
0.43u
Supposed to be 15.5. Will have it graded correctly if loses. Pitching system: Faded Vazquez. Ticket tweeted and on pikkit
Top Shelf Action 🥃
Last 30d: 203-181-3 (+2.4u)
R.Vasquez u3.5 Ks+120
0.37u
1.88% ev
The Pick Don
Last 30d: 19-9-0 (+11.1u)
CHC -0.5 (F5)-115
1.5u
Chris Gimino
Last 30d: 21-33-1 (-12.5u)
R.Vasquez u3.5 Ks+120
1.2u
Steak Friend
Last 30d: 0-0-0 (+0.0u)
SD +143
1u
Sandy Plashkes
Last 30d: 101-122-2 (-22.4u)
CHC -0.5 (F5)-120
1u
💰🦡 Jake
Last 30d: 107-110-10 (+5.7u)
Under 3.5 (F5)-105
1.05u
Brian Bitler
Last 30d: 82-82-2 (-9.4u)
CHC -160
1.88u
Cam Is Money
Last 30d: 84-81-1 (+5.4u)
M.Busch u0.5 Hits+120
1.2u
Austin Pendergrass
Last 30d: 46-51-0 (-8.2u)
Under 0.5 (1st Inn)-146
0.5u
Moneyline Hacks
Last 30d: 130-139-2 (+48.7u)
Under 6.5+105
1.05u
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Allan Lem
Last 30d: 168-114-2 (+16.3u)
R.Vasquez u2.5 BB-150
0.75u
Vasquez is coming off a 4-walk performance but I’m viewing this as a bounce-back spot. He made huge leaps last year in control, finishing with a 6.7% BB% which meant a 2.6 BB/9 ratio. Most season-long projection systems have Vazquez closer to a 3.2 BB/9 pitcher this season, which means if he pitched 6 innings you’d expect around 2.2 walks.
This isn’t a great matchup as the Cubs have been hot and were a top-10 team in walk rate last season, but I have this projected closer to 2.2 walks and am trusting the longer sample of him as a pitcher.

Sean Zerillo
Last 30d: 60-93-2 (-1.4u)
Under 7-125
0.25u
Bet to -130; split with Under 6.5 (bigger edge on plus than juiced 7)
Under 6.5+110
0.28u
Bet to -110; bigger edge at plus money compared to 7 (-125)
DeadPresPicks
Last 30d: 9-16-0 (-1.2u)
CHC -158
0.47u
Padres vs. Cubs Previews & Analysis
Prop Odds Comparison
Line Movement Tracker
Padres vs. Cubs Public Betting Percentages
Betting Trends
- Cubs are 4-1 in their last 5 games.
- Cubs are 4-1 in their last 5 games against the spread
- Cubs are 39-42 in their road games against the spread
- The totals have gone OVER in 4 of Cubs' last 5 games
- The totals have gone OVER in 40 of Cubs' 81 last games at home
Matchup History
Against the Spread (ATS) History
Over/Under History
Last 5 Matchups
Cubs vs. Padres Injury Updates

Cubs Injuries
- Justin SteeleSP
Steele is out for season with elbow
Out for Season

Padres Injuries
- Joe MusgroveSP
Musgrove is out for season with elbow
Out for Season
Padres vs. Cubs Box Score
Padres Player Stats| PITCHER | PC | IP | K | ER | |
|---|---|---|---|---|---|
![]() | 82 | 4.2 | 2 | 2 | |
![]() | 19 | 0.2 | 1 | 0 | |
![]() | 26 | 1.2 | 1 | 0 | |
![]() | 13 | 1 | 1 | 0 |
| HITTERS | H-AB | R | HR | RBI |
|---|---|---|---|---|
![]() | 2-4 | 0 | 0 | 0 |
![]() | 0-4 | 0 | 0 | 0 |
![]() | 0-4 | 0 | 0 | 0 |
![]() | 0-3 | 0 | 0 | 0 |
![]() | 2-4 | 0 | 0 | 0 |
![]() | 0-3 | 0 | 0 | 0 |
![]() | 0-1 | 0 | 0 | 0 |
![]() | 1-4 | 0 | 0 | 0 |
![]() | 0-2 | 0 | 0 | 0 |
![]() | 1-2 | 1 | 1 | 1 |
![]() | 0-1 | 0 | 0 | 0 |
![]() | 0-1 | 0 | 0 | 0 |
Cubs Player Stats| PITCHER | PC | IP | K | ER | |
|---|---|---|---|---|---|
![]() | 91 | 7.1 | 4 | 1 | |
![]() | 15 | 0.2 | 1 | 0 | |
![]() | 33 | 1 | 1 | 0 |
| HITTERS | H-AB | R | HR | RBI |
|---|---|---|---|---|
![]() | 2-4 | 2 | 0 | 0 |
![]() | 0-2 | 1 | 0 | 0 |
![]() | 0-3 | 0 | 0 | 0 |
![]() | 0-1 | 0 | 0 | 0 |
![]() | 1-1 | 0 | 0 | 1 |
![]() | 1-1 | 0 | 0 | 1 |
![]() | 0-3 | 0 | 0 | 0 |
![]() | 0-3 | 0 | 0 | 1 |
![]() | 0-4 | 0 | 0 | 0 |
![]() | 0-3 | 0 | 0 | 0 |
![]() | 0-4 | 0 | 0 | 0 |
Padres vs. Cubs Odds Comparison
Could not load odds
Padres at Cubs Team Totals
MatchupOverUnder | ||
|---|---|---|
Padres 1-2 | o2.5-145 | u2.5+114 |
Cubs 4-4 | o3.5-127 | u3.5-101 |






























