White Sox vs. Cubs Odds & Betting Predictions - May 16, 2025

White Sox at Cubs

6:20 pm • CHSN

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Chicago White Sox

@

Chicago Cubs

pitcher		team	era	w-l
C.Horton			0.00	0-0
S.Smith			0.00	0-0

MatchupOpenSpreadTotalMoneyline
White Sox 14-29	+1.5	+1.5-114	o12.5-124	+172
Cubs 25-19	u12.5	-1.5-105	u12.5+102	-205

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Friday 6:20 p.m.

May 16, 2025

Wrigley FieldChicago

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81°Fahrenheit

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15Wind

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MLB Public Betting

Cubs are 3-2 in their last 5 games.
Cubs are 2-3 in their last 5 games against the spread
Cubs are 12-10 in their road games against the spread
The totals have gone OVER in 2 of Cubs' last 5 games
The totals have gone OVER in 14 of Cubs' 22 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Cubs	22-22	10-12	12-10	13-12	9-10
White Sox	24-19	11-10	13-9	N/A	24-19

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Cubs	25-17-2	14-8	11-9-2	13-11-1	12-6-1
White Sox	19-22-2	11-8-2	8-14	N/A	19-22-2

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Cubs	25-19	12-10	13-9	16-9	9-10
White Sox	14-29	9-12	5-17	N/A	14-29

date	opponent	score	spread	over/under	moneyline
May 14th	MIA	L 1-3	-1.5 L	U 7.5	MIA -218
May 13th	MIA	W 5-4	-1.5 L	O 8	CHC -262
May 12th	MIA	W 5-2	-1.5 W	U 8	CHC -257
May 11th	@NYM	L 2-6	+1.5 L	U 8.5	NYM +110
May 10th	@NYM	W 6-5	+1.5 W	O 8.5	CHC +141

Ky Bush
P
Bush is out with elbow
Out
Chase Meidroth
IF
Meidroth is day-to-day with thumb
Day-to-Day
Drew Thorpe
P
Thorpe is out with elbow
Out

Drew Pomeranz
P
Pomeranz is out with elbow
Out
Justin Steele
P
Steele is out for season with elbow
Out for Season

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MatchupOverUnder
White Sox 14-29	N/A	N/A
Cubs 25-19	N/A	N/A